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Personal or first-degree family breast cancer history: which has higher impact on tumor detection and tumor size in breast cancer

Schwab, Fabienne ; Kilic, Nerbil ; Huang, Dorothy ; Schmid, Seraina ; Vetter, Marcus ; Schötzau, Andreas ; Güth, Uwe

In: Archives of Gynecology and Obstetrics, 2015, vol. 291, no. 6, p. 1387-1394

Adenocarcinomas of the upper third of the rectum and the rectosigmoid junction seem to have similar prognosis as colon cancers even without radiotherapy, SAKK 40/87

Käser, S. ; Froelicher, J. ; Li, Q. ; Müller, S. ; Metzger, U. ; Castiglione, M. ; Laffer, U. ; Maurer, C.

In: Langenbeck's Archives of Surgery, 2015, vol. 400, no. 6, p. 675-682

Efficacy, effectiveness and safety of long-acting granulocyte colony-stimulating factors for prophylaxis of chemotherapy-induced neutropenia in patients with cancer: a systematic review

Pfeil, Alena ; Allcott, Kim ; Pettengell, Ruth ; von Minckwitz, Gunter ; Schwenkglenks, Matthias ; Szabo, Zsolt

In: Supportive Care in Cancer, 2015, vol. 23, no. 2, p. 525-545

Selektive Östrogenrezeptormodulatoren (SERM) = Selective estrogen receptor modulators (SERM)

Stute, Petra ; Birkhäuser, Martin

In: Gynäkologische Endokrinologie, 2015, vol. 13, no. 2, p. 126-134

High tumor budding stratifies breast cancer with metastatic properties

Salhia, Bodour ; Trippel, Mafalda ; Pfaltz, Katrin ; Cihoric, Nikola ; Grogg, André ; Lädrach, Claudia ; Zlobec, Inti ; Tapia, Coya

In: Breast Cancer Research and Treatment, 2015, vol. 150, no. 2, p. 363-371

Breast cancer and pregnancy

Knabben, Laura ; Mueller, Michel D.

In: Hormone Molecular Biology and Clinical Investigation, 2017, vol. 32, no. 1, p. -

TGFBI modulates tumour hypoxia and promotes breast cancer metastasis

Fico, Flavia ; Santamaria‐Martínez, Albert

In: Molecular Oncology, 2020, vol. 14, no. 12, p. 3198–3210

Breast cancer metastasis is a complex process that depends not only on intrinsic characteristics of metastatic stem cells, but also on the particular microenvironment that supports their growth and modulates the plasticity of the system. In search for microenvironmental factors supporting cancer stem cell (CSC) growth and tumour progression to metastasis, we here investigated the role of the...

Innate immune cells and their contribution to T-cell-based immunotherapy

Ginefra, Pierpaolo ; Lorusso, Girieca ; Vannini, Nicola

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 12, p. 4441

In recent years, immunotherapy has become the most promising therapy for a variety of cancer types. The development of immune checkpoint blockade (ICB) therapies, the adoptive transfer of tumor-specific T cells (adoptive cell therapy (ACT)) or the generation of T cells engineered with chimeric antigen receptors (CAR) have been successfully applied to elicit durable immunological responses in...

Changes in breast cancer management during the Corona Virus Disease 19 pandemic : an international survey of the European Breast Cancer Research Association of Surgical Trialists (EUBREAST)

Gasparri, Maria Luisa ; Gentilini, Oreste Davide ; Lueftner, Diana ; Kuehn, Thorsten ; Kaidar-Person, Orit ; Poortmans, Philip

In: The breast, 2020, vol. 52, p. 110-115

Background: Corona Virus Disease 19 (COVID-19) had a worldwide negative impact on healthcare systems, which were not used to coping with such pandemic. Adaptation strategies prioritizing COVID-19 patients included triage of patients and reduction or re-allocation of other services. The aim of our survey was to provide a real time international snapshot of modifications of breast cancer...

Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer

Alday-Parejo, Begoña ; Richard, François ; Wörthmüller, Janine ; Rau, Tilman ; Galván, José A. ; Desmedt, Christine ; Santamaria-Martinez, Albert ; Rüegg, Curzio

In: Cancers, 2020, vol. 12, no. 1, p. 223

Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...