In: Bioinformatics, 2017, vol. 33, no. 19, p. 3123-3125
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In: Bioinformatics, 2016, vol. 32, no. 10, p. 1479-1485
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In: Journal of the American Medical Informatics Association, 2017, vol. 24, no. 4, p. 799-805
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In: Brain, 2016, vol. 139, no. 6, p. 1855-1861
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In: Briefings in Bioinformatics, 2017, vol. 18, no. 2, p. 205-214
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In: Human Molecular Genetics, 2018, vol. 27, no. 4, p. 732-741
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In: Bioinformatics, 2017, vol. 33, no. 12, p. 1895-1897
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In: Nature, 2016, vol. 529, p. 25 p
Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability provide the pathogen with a powerful means of escape from host antibodies1,2,3,4. Although broadly reactive antibodies against these antigens could be useful as therapeutics and in vaccine design, their...
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In: Genetics, 2020, vol. 216, no. 4, p. 931–945
Differential gene expression across cell types underlies development and cell physiology in multicellular organisms. Caenorhabditis elegans is a powerful, extensively used model to address these biological questions. A remaining bottleneck relates to the difficulty to obtain comprehensive tissue-specific gene transcription data, since available methods are still challenging to execute and/or...
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In: Molecular Ecology Resources, 2020, vol. 20, no. 4, p. 856–870
In non-model organisms, evolutionary questions are frequently addressed using reduced representation sequencing techniques due to their low cost, ease of use, and because they do not require genomic resources such as a reference genome. However, evidence is accumulating that such techniques may be affected by specific biases, questioning the accuracy of obtained genotypes, and as a...
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