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Percutaneous Endovascular Salvage Techniques for Implanted Venous Access Device Dysfunction

Breault, Stéphane ; Glauser, Frédéric ; Babaker, Malik ; Doenz, Francesco ; Qanadli, Salah

In: CardioVascular and Interventional Radiology, 2015, vol. 38, no. 3, p. 642-650

Knee arthrodesis with modular nail after failed TKA due to infection

Gallusser, Nicolas ; Goetti, Patrick ; Luyet, Anais ; Borens, Olivier

In: European Journal of Orthopaedic Surgery & Traumatology, 2015, vol. 25, no. 8, p. 1307-1312

Sarcoma of the heart: survival after surgery

Niclauss, Lars ; Montemurro, Michael ; Kirsch, Matthias ; Prêtre, René

In: Interactive CardioVascular and Thoracic Surgery, 2018, vol. 27, no. 2, p. 198-201

Pyriform sinus squamous cell carcinoma: oncological outcomes in good responders of induction chemotherapy-based larynx preservation protocols

Vourexakis, Zacharias ; Le Ridant, Anne-Marie ; Dulguerov, Pavel ; Janot, François

In: European Archives of Oto-Rhino-Laryngology, 2015, vol. 272, no. 7, p. 1725-1731

TGFBI modulates tumour hypoxia and promotes breast cancer metastasis

Fico, Flavia ; Santamaria‐Martínez, Albert

In: Molecular Oncology, 2020, vol. 14, no. 12, p. 3198–3210

Breast cancer metastasis is a complex process that depends not only on intrinsic characteristics of metastatic stem cells, but also on the particular microenvironment that supports their growth and modulates the plasticity of the system. In search for microenvironmental factors supporting cancer stem cell (CSC) growth and tumour progression to metastasis, we here investigated the role of the...

Targeting GATA transcription factors – a novel strategy for anti-aging interventions?

Zimmermann, Andreas ; Kainz, Katharina ; Hofer, Sebastian J. ; Bauer, Maria A. ; Schroeder, Sabrina ; Dengjel, Jörn ; Pietrocola, Federico ; Kepp, Oliver ; Ruckenstuhl, Christoph ; Eisenberg, Tobias ; Sigrist, Stephan J. ; Madeo, Frank ; Kroemer, Guido ; Carmona-Gutierrez, Didac

In: Microbial Cell, 2019, vol. 6, no. 5, p. 212–216

GATA transcription factors (TFs) constitute a conserved family of zinc-finger TFs that fulfill diverse functions across eukaryotes. Accumulating evidence suggests that GATA TFs also play a role in lifespan regulation. In a recent study, we identified a natural polyphenol, 4,4’-dimethoxychalcone (DMC), that extends lifespan depending on reduced activity of distinct GATA TFs. Prolonged...

Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma

Jacquelot, Nicolas ; Enot, David P. ; Flament, Caroline ; Vimond, Nadège ; Blattner, Carolin ; Pitt, Jonathan M. ; Yamazaki, Takahiro ; Roberti, María Paula ; Daillère, Romain ; Vétizou, Marie ; Poirier-Colame, Vichnou ; Semeraro, Michaëla ; Caignard, Anne ; Slingluff Jr., Craig L. ; Sallusto, Federica ; Rusakiewicz, Sylvie ; Weide, Benjamin ; Marabelle, Aurélien ; Kohrt, Holbrook ; Dalle, Stéphane ; Cavalcanti, Andréa ; Kroemer, Guido ; Di Giacomo, Anna Maria ; Maio, Michele ; Wong, Phillip ; Yuan, Jianda ; Wolchok, Jedd ; Umansky, Viktor ; Eggermont, Alexander ; Zitvogel, Laurence

In: The journal of clinical investigation, 2016, vol. 126, no. 3, p. 921-937

Melanoma prognosis is dictated by tumor-infiltrating lymphocytes, the migratory and functional behavior of which is guided by chemokine or cytokine gradients. Here, we retrospectively analyzed the expression patterns of 9 homing receptors (CCR/CXCR) in naive and memory CD4+ and CD8+ T lymphocytes in 57 patients with metastatic melanoma (MMel) with various sites of metastases to evaluate...

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Carmona-Gutierrez, Didac ; Zimmermann, Andreas ; Kainz, Katharina ; Pietrocola, Federico ; Chen, Guo ; Maglioni, Silvia ; Schiavi, Alfonso ; Nah, Jihoon ; Mertel, Sara ; Beuschel, Christine B. ; Castoldi, Francesca ; Sica, Valentina ; Trausinger, Gert ; Raml, Reingard ; Sommer, Cornelia ; Schroeder, Sabrina ; Hofer, Sebastian J. ; Bauer, Maria A. ; Pendl, Tobias ; Tadic, Jelena ; Dammbrueck, Christopher ; Hu, Zehan ; Ruckenstuhl, Christoph ; Eisenberg, Tobias ; Durand, Sylvere ; Bossut, Noélie ; Aprahamian, Fanny ; Abdellatif, Mahmoud ; Sedej, Simon ; Enot, David P. ; Wolinski, Heimo ; Dengjel, Jörn ; Kepp, Oliver ; Magnes, Christoph ; Sinner, Frank ; Pieber, Thomas R. ; Sadoshima, Junichi ; Ventura, Natascia ; Sigrist, Stephan J. ; Kroemer, Guido ; Madeo, Frank

In: Nature Communications, 2019, vol. 10, no. 1, p. 651

Ageing constitutes the most important risk factor for all major chronic ailments, including malignant, cardiovascular and neurodegenerative diseases. However, behavioural and pharmacological interventions with feasible potential to promote health upon ageing remain rare. Here we report the identification of the flavonoid 4,4′- dimethoxychalcone (DMC) as a natural compound with anti-ageing...

Radio-frequency tissue ablation of the liver: in vivo and ex vivo experiments with four different systems

Denys, Alban ; Baere, Thierry ; Kuoch, Viseth ; Dupas, Benoit ; Chevallier, Patrick ; Madoff, David ; Schnyder, Pierre ; Doenz, Francesco

In: European Radiology, 2003, vol. 13, no. 10, p. 2346-2352

Late solitary bone metastasis of a primary pulmonary synovial sarcoma with SYT-SSX1 translocation type: case report with a long follow-up

Bode-Lesniewska, B. ; Hodler, J. ; von Hochstetter, A. ; Guillou, L. ; Exner, U. ; Caduff, R.

In: Virchows Archiv, 2005, vol. 446, no. 3, p. 310-315