In: The Journal of Clinical Endocrinology & Metabolism, 2018, vol. 103, no. 9, p. 3466-3476
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In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 6, p. 2348-2357
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In: Cancer Immunology, Immunotherapy, 2015, vol. 64, no. 5, p. 635-644
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In: European Radiology, 2015, vol. 25, no. 12, p. 3499-3507
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In: Rheumatology International, 2015, vol. 35, no. 2, p. 295-302
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In: Diabetologia, 2015, vol. 58, no. 3, p. 558-565
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In: Rheumatology International, 2015, vol. 35, no. 10, p. 1641-1654
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In: Frontiers in Bioengineering and Biotechnology, 2020, vol. 8, p. -
A large number of prevalent lung diseases is associated with tissue inflammation. Clinically, corticosteroid therapies are applied systemically or via inhalation for the treatment of lung inflammation, and a number of novel therapies are being developed that require preclinical testing. In alveoli, macrophages and dendritic cells play a key role in initiating and diminishing pro-inflammatory...
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In: Frontiers in immunology, 2019, vol. 10, p. 1391
Pemphigus vulgaris (PV) is an autoimmune bullous disease of the skin and mucous membranes characterized by the presence of circulating and tissue-bound autoantibodies against keratinocyte cell surface antigens, specifically desmoglein (Dsg) 1 and 3. The pathogenic role of anti-Dsg antibodies is well-established, while the mechanism of blister formation is only partly defined. We have applied...
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In: Oncotarget, 2015, vol. 6, no. 32, p. 33823-33833
The T cell immunoglobulin and mucin domain 3 (Tim-3) is a plasma membrane-associated receptor which is involved in a variety of biological responses in human immune cells. It is highly expressed in most acute myeloid leukaemia (AML) cells and therefore may serve as a possible target for AML therapy. However, its biochemical activities in primary human AML cells remain unclear. We therefore...
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