In: Bioinformatics, 2016, vol. 32, no. 14, p. 2111-2119
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In: Glycobiology, 2017, vol. 27, no. 6, p. 525-535
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In: PLOS Genetics, 2020, vol. 16, no. 10, p. e1009102
Ryanodine receptors (RyR) are essential regulators of cellular calcium homeostasis and signaling. Vertebrate genomes contain multiple RyR gene isoforms, expressed in different tissues and executing different functions. In contrast, invertebrate genomes contain a single RyR-encoding gene and it has long been proposed that different transcripts generated by alternative splicing may diversify...
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In: The EMBO Journal, 2020, vol. 39, no. 19, p. e103889
Plasticity of the proteome is critical to adapt to varying conditions. Control of mitochondrial protein import contributes to this plasticity. Here, we identified a pathway that regulates mitochondrial protein import by regulated N-terminal processing. We demonstrate that dipeptidyl peptidases 8/9 (DPP8/9) mediate the N-terminal processing of adenylate kinase 2 (AK2) en route to mitochondria....
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In: Scientific Reports, 2020, vol. 10, no. 1, p. 8268
Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. The importance of SPL-mediated ethanolamine phosphate formation has been characterized in only...
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In: Amino Acids, 2014, vol. 46, no. 7, p. 1775-1783
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In: Journal of Biomolecular NMR, 2010, vol. 46, no. 1, p. 51-65
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In: Molecular Biology Reports, 2010, vol. 37, no. 7, p. 3503-3508
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In: Cellular and Molecular Life Sciences, 2011, vol. 68, no. 21, p. 3469-3478
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In: Apoptosis, 2007, vol. 12, no. 11, p. 2051-2061
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