Consortium of Swiss Academic Libraries

Call for reviews on global health challenges

Yap, Peiling ; Waiswa, Peter ; Berger, Anke ; Künzli, Nino

In: International Journal of Public Health, 2015, vol. 60, no. 7, p. 753-754

Consortium of Swiss Academic Libraries

Erratum to: Global standards for global health in a globalized economy!

Künzli, Nino ; Kutlar Joss, Meltem ; Gintowt, Emily

In: International Journal of Public Health, 2015, vol. 60, no. 8, p. 999-1000

Consortium of Swiss Academic Libraries

Global standards for global health in a globalized economy!

Künzli, Nino ; Joss, Meltem ; Gintowt, Emily

In: International Journal of Public Health, 2015, vol. 60, no. 7, p. 757-759

Université de Fribourg

Mitochondrial sphingosine-1-phosphate lyase is essential for phosphatidylethanolamine synthesis and survival of Trypanosoma brucei

Dawoody Nejad, Ladan ; Stumpe, Michael ; Rauch, Monika ; Hemphill, Andrew ; Schneiter, Roger ; Bütikofer, Peter ; Serricchio, Mauro

In: Scientific Reports, 2020, vol. 10, no. 1, p. 8268

Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. The importance of SPL-mediated ethanolamine phosphate formation has been characterized in only...

Università della Svizzera italiana

Sedentary behaviour in Swiss children and adolescents : disentangling associations with the perceived and objectively measured environment

Bringolf-Isler, Bettina ; De Hoogh, Kees ; Schindler, Christian ; Kayser, Bengt ; Suggs, L. Suzanne ; Dössegger, Alain ; Probst-Hensch, Nicole ; The SOPHYA Study Group

In: International journal of environmental research and public health, 2018, vol. 15, no. 5, p. 918

Identifying correlates of sedentary behaviour across all levels of the ecological model and understanding their interrelations is a promising method to plan effective interventions. The present study examined whether the objectively assessed and the perceived neighbourhood are associated with children’s sedentary behaviour time (SBT). A comprehensive set of factors at different levels of...

Université de Fribourg

Initial viral inoculum determines kinapse-and synapse-like t cell motility in reactive lymph nodes

Sivapatham, Sujana ; Ficht, Xenia ; Albuquerque, Juliana Barreto de ; Page, Nicolas ; Merkler, Doron ; Stein, Jens V.

In: Frontiers in Immunology, 2019, vol. 10, p. -

T cell activation in lymphoid tissue occurs through interactions with cognate peptide- major histocompatibility complex (pMHC)-presenting dendritic cells (DCs). Intravital imaging studies using ex vivo peptide-pulsed DCs have uncovered that cognate pMHC levels imprint a wide range of dynamic contacts between these two cell types. T cell—DC interactions vary between transient,...

Università della Svizzera italiana

Macrophage death following influenza vaccination initiates the inflammatory response that promotes dendritic cell function in the draining lymph node

Chatziandreou, Nikolaos ; Farsakoglu, Yagmur ; Palomino-Segura, Miguel ; D’Antuono, Rocco ; Pizzagalli, Diego Ulisse ; Sallusto, Federica ; Lukacs-Kornek, Veronika ; Uguccioni, Mariagrazia ; Corti, Davide ; Turley, Shannon J. ; Lanzavecchia, Antonio ; Carroll, Michael C. ; Gonzalez, Santiago F.

In: Cell reports, 2017, vol. 18, no. 10, p. 2427-2440

The mechanism by which inflammation influences the adaptive response to vaccines is not fully understood. Here, we examine the role of lymph node macrophages (LNMs) in the induction of the cytokine storm triggered by inactivated influenza virus vaccine. Following vaccination, LNMs undergo inflammasome-independent necrosis-like death that is reliant on MyD88 and Toll-like receptor 7 (TLR7)...