Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.
Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...
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In: European Archives of Psychiatry and Clinical Neuroscience, 2015, vol. 265, no. 5, p. 407-417
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In: Cerebral Cortex, 2016, vol. 26, no. 3, p. 943-949
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In: Zeitschrift für Gerontologie und Geriatrie, 2015, vol. 48, no. 1, p. 15-21
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In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 12, p. 4945-4954
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In: Cerebral Cortex, 2018, vol. 28, no. 12, p. 4365-4378
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In: Cognitive, Affective, & Behavioral Neuroscience, 2015, vol. 15, no. 4, p. 878-888
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In: Acta Neurochirurgica, 2015, vol. 157, no. 9, p. 1449-1458
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In: Journal of Neural Transmission, 2020, vol. 127, no. 1, p. 103–115
Working memory (WM) deficits constitute a core symptom of schizophrenia. Inadequacy of WM maintenance in schizophrenia has been reported to reflect abnormalities in the excitation/inhibition (E/I) balance between pyramidal neurons and parvalbumin basket cells, which may explain alterations of the dynamics of gamma and delta oscillations. To address this issue, we assessed event-related gamma...
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In: Brain and Behavior, 2019, no. 9, p. 1-21
Introduction: Reward and stress are important determinants of motivated behaviors. Striatal regions play a crucial role in both motivation and hedonic processes. So far, little is known on how cognitive effort interacts with stress to modulate reward processes. This study examines how cognitive effort (load) interacts with an unpredictable acute stressor (threat-of-shock) to modulate motivational...
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