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In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases

Singovski, Grigori ; Bernal, Carolina ; Kuciak, Monika ; Siegl-Cachedenier, Irene ; Conod, Arwen ; Ruiz i Altaba, Ariel

In: Journal of Molecular Cell Biology, 2016, vol. 8, no. 2, p. 157-173

Bovine lactoferrin-induced CCL1 expression involves distinct receptors in monocyte-derived dendritic cells and their monocyte precursors

Latorre, Daniela ; Pulvirenti, Nadia ; Covino, Daniela Angela ; Varano, Barbara ; Purificato, Cristina ; Rainaldi, Gabriella ; Gauzzi, Maria Cristina ; Fantuzzi, Laura ; Conti, Lucia ; Donninelli, Gloria ; Del Cornò, Manuela ; Sabbatucci, Michela ; Gessani, Sandra ; Puddu, Patrizia

In: Toxins, 2015, vol. 7, no. 12, p. 5472-5483

Lactoferrin (LF) exhibits a wide range of immunomodulatory activities including modulation of cytokine and chemokine secretion. In this study, we demonstrate that bovine LF (bLF) up-modulates, in a concentration- and time-dependent manner, CCL1 secretion in monocytes (Mo) at the early stage of differentiation toward dendritic cells (DCs), and in fully differentiated immature Mo-derived DCs...

Characterization of variable regions of the Gp120 protein from HIV-1 subtype C virus variants obtained from individuals at different disease stages in Sub-Saharan Africa

Cenci, A. ; Tavoschi, L. ; D'Avenio, G. ; Narino, P. ; Becattini, S. ; Bernasconi, D. ; Chiappi, M. ; La Torre, L. ; Sukati, H. ; Vardas, E. ; Lo Presti, A. ; Cella, E. ; Ciccozzi, M. ; Picconi, O. ; Monini, P. ; Ensoli, B. ; Buttò, S.

In: Journal of AIDS & clinical research, 2012, vol. S8:006, p. 1-10

Background: The development of a vaccine against HIV/AIDS capable of preventing virus infection has been hampered by the HIV envelope (Env) heterogeneity that makes it difficult to induce neutralizing antibodies against Env proteins from different HIV clades. Several studies have indicated that gp120 Env protein sequence tends to change considerably during the course of HIV disease which...

Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma

Drecoll, Enken ; Nitsche, Ulrich ; Bauer, Karina ; Berezowska, Sabina ; Slotta-Huspenina, Julia ; Rosenberg, Robert ; Langer, Rupert

In: International Journal of Colorectal Disease, 2014, vol. 29, no. 6, p. 663-671

The Evolution of Virulence in RNA Viruses underaCompetition-Colonization Trade-Off

Delgado-Eckert, Edgar ; Ojosnegros, Samuel ; Beerenwinkel, Niko

In: Bulletin of Mathematical Biology, 2011, vol. 73, no. 8, p. 1881-1908

Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation

Bouzourene, Hanifa ; Hutter, Pierre ; Losi, Lorena ; Martin, Patricia ; Benhattar, Jean

In: Familial Cancer, 2010, vol. 9, no. 2, p. 167-172

Double frameshift mutations in APC and MSH2 in the same individual

Soravia, Claudio ; DeLozier, Celia ; Dobbie, Zuzana ; Berthod, Claudine ; Arrigoni, Eviano ; Bründler, Marie-Anne ; Blouin, Jean-Louis ; Foulkes, William ; Hutter, Pierre

In: International Journal of Colorectal Disease, 2005, vol. 20, no. 5, p. 466-470

TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis

Somasekharan, Syam ; Koc, Michal ; Morizot, Alexandre ; Micheau, Olivier ; Sorensen, Poul ; Gaide, Olivier ; Andera, Ladislav ; Martinou, Jean-Claude

In: Apoptosis, 2013, vol. 18, no. 3, p. 324-336

PI3Kinase signaling in glioblastoma

Lino, M. ; Merlo, A.

In: Journal of Neuro-Oncology, 2011, vol. 103, no. 3, p. 417-427

DNA repair nucleases

Marti, T. ; Fleck, O.

In: Cellular and Molecular Life Sciences CMLS, 2004, vol. 61, no. 3, p. 336-354