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Intrinsic rifamycin resistance of Mycobacterium abscessus is mediated by ADP-ribosyltransferase MAB_0591

Rominski, Anna ; Roditscheff, Anna ; Selchow, Petra ; Böttger, Erik C. ; Sander, Peter

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 2, p. 376-384

Elucidation of Mycobacterium abscessus aminoglycoside and capreomycin resistance by targeted deletion of three putative resistance genes

Rominski, Anna ; Selchow, Petra ; Becker, Katja ; Brülle, Juliane K. ; Dal Molin, Michael ; Sander, Peter

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 8, p. 2191-2200

Comment on: Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system

Imkamp, Frank ; Keller, Peter M. ; Böttger, Erik C.

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 12, p. 3624-3624

Effect of β-lactamase production and β-lactam instability on MIC testing results for Mycobacterium abscessus

Rominski, Anna ; Schulthess, Bettina ; Müller, Daniel M. ; Keller, Peter M. ; Sander, Peter

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 11, p. 3070-3078

Biological and clinical implications of BIRC3 mutations in chronic lymphocytic leukemia

Diop, Fary ; Moia, Riccardo ; Favini, Chiara ; Spaccarotella, Elisa ; De Paoli, Lorenzo ; Bruscaggin, Alessio ; Spina, Valeria ; Terzi-di-Bergamo, Lodovico ; Arruga, Francesca ; Tarantelli, Chiara ; Deambrogi, Clara ; Rasi, Silvia ; Adhinaveni, Ramesh ; Patriarca, Andrea ; Favini, Simone ; Sagiraju, Sruthi ; Jabangwe, Clive ; Kodipad, Ahad A. ; Peroni, Denise ; Mauro, Francesca R. ; Del Giudice, Ilaria ; Forconi, Francesco ; Cortelezzi, Agostino ; Zaja, Francesco ; Bomben, Riccardo ; Rossi, Francesca Maria ; Visco, Carlo ; Chiarenza, Annalisa ; Rigolin, Gian Matteo ; Marasca, Roberto ; Coscia, Marta ; Perbellini, Omar ; Tedeschi, Alessandra ; Laurenti, Luca ; Motta, Marina ; Donaldson, David ; Weir, Phil ; Mills, Ken ; Thornton, Patrick ; Lawless, Sarah ; Bertoni, Francesco ; Del Poeta, Giovanni ; Cuneo, Antonio ; Follenzi, Antonia ; Gattei, Valter ; Boldorini, Renzo Luciano ; Catherwood, Mark ; Deaglio, Silvia ; Foà, Robin ; Gaidano, Gianluca ; Rossi, Davide

In: Haematologica, 2020, vol. 105, no. 2, p. 448-456

BIRC3 is a recurrently mutated gene in chronic lymphocytic leukemia (CLL) but the functional implications of BIRC3 mutations are largely unexplored. Furthermore, little is known about the prognostic impact of BIRC3 mutations in CLL cohorts homogeneously treated with first-line fludarabine, cyclophosphamide, and rituximab (FCR). By immunoblotting analysis, we showed that the non-canonical...

miR-146a and NF-κB1 regulate mast cell survival and T lymphocyte differentiation

Rusca, Nicole ; Dehò, Lorenzo ; Montagner, Sara ; Zielinski, Christina E. ; Sica, Antonio ; Sallusto, Federica ; Monticelli, Silvia

In: Molecular and cellular biology, 2012, vol. 32, no. 21, p. 4432-4444

The transcription factor NF-κB regulates the expression of a broad number of genes central to immune and inflammatory responses. We identified a new molecular network that comprises specifically the NF-κB family member NF-κB1 (p50) and miR-146a, and we show that in mast cells it contributes to the regulation of cell homeostasis and survival, while in T lymphocytes it modulates T cell...

Effects of monoamines and antidepressants on astrocyte physiology: implications for monoamine hypothesis of depression

Marathe, Swananda V ; D’almeida, Priyal L ; Virmani, Garima ; Bathini, Praveen ; Alberi, Lavinia

In: Journal of Experimental Neuroscience, 2018, vol. 12, p. -

Major depressive disorder (MDD) is one of the most common neuropsychiatric disorders affecting over one-fifth of the population worldwide. Owing to our limited understanding of the pathophysiology of MDD, the quest for finding novel antidepressant drug targets is severely impeded. Monoamine hypothesis of MDD provides a robust theoretical framework, forming the core of a large jigsaw puzzle, ...

Polymorphisms in Toll-like receptor 4 ( TLR4 ) are associated with protection against leprosy

Bochud, P.-Y ; Sinsimer, D. ; Aderem, A. ; Siddiqui, M. ; Saunderson, P. ; Britton, S. ; Abraham, I. ; Tadesse Argaw, A. ; Janer, M. ; Hawn, T. ; Kaplan, G.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2009, vol. 28, no. 9, p. 1055-1065

Tuberculosis: drug resistance, fitness, and strategies for global control

Böttger, Erik ; Springer, Burkhard

In: European Journal of Pediatrics, 2008, vol. 167, no. 2, p. 141-148

Disseminated Tuberculosis Following Total Knee Arthroplasty in an HIV Patient

Marschall, J. ; Evison, J.-M ; Droz, S. ; Studer, U. ; Zimmerli, S.

In: Infection, 2008, vol. 36, no. 3, p. 274-278