In: Basic Research in Cardiology, 2015, vol. 110, no. 1, p. 1-17
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In: Human Reproduction Update, 2016, vol. 22, no. 3, p. 382-403
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In: European Journal of Applied Physiology, 2015, vol. 115, no. 7, p. 1417-1427
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In: The International Journal of Cardiovascular Imaging, 2015, vol. 31, no. 7, p. 1425-1434
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In: European Journal of Applied Physiology, 2015, vol. 115, no. 10, p. 2107-2114
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In: Cardiovascular Research, 2016, vol. 109, no. 1, p. 103-114
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In: Human Molecular Genetics, 2017, vol. 26, no. 2, p. 320-332
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In: Cells, 2020, vol. 9, no. 7, p. 1695
The aged population is currently at its highest level in human history and is expected to increase further in the coming years. In humans, aging is accompanied by impaired angiogenesis, diminished blood flow and altered metabolism, among others. A cellular mechanism that impinges upon these manifestations of aging can be a suitable target for therapeutic intervention. Here we identify cell...
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In: Current Opinion in Physiology, 2020, vol. 14, p. 21–26
Among adult vertebrates, the zebrafish presents the rather exceptional capacity to efficiently regenerate its heart after injury. This bony fish has thus become a leading genetic model organism to elucidate the natural mechanisms of successful cardiac restoration. Given its potential biomedical significance, parallel analyses between zebrafish and mammals are aiming at the identification of...
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In: npj Regenerative Medicine, 2019, vol. 4, no. 1, p. 2
Unlike mammals, adult zebrafish can regenerate their hearts after injury via proliferation of cardiomyocytes. The cell-cycle entry of zebrafish cardiac cells can also be stimulated through preconditioning by thoracotomy, a chest incision without myocardial damage. To identify effector genes of heart preconditioning, we performed transcriptome analysis of ventricles from thoracotomized...
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