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Università della Svizzera italiana

Exon–Intron differential analysis reveals the role of competing endogenous RNAs in post-transcriptional regulation of translation

Munz, Nicolas ; Cascione, Luciano ; Parmigiani, Luca ; Tarantelli, Chiara ; Rinaldi, Andrea ; Cmiljanovic, Natasa ; Cmiljanovic, Vladimir ; Giugno, Rosalba ; Bertoni, Francesco ; Napoli, Sara

In: Non-coding RNA, 2021, vol. 7, no. 2, p. 13

Stressful conditions induce the cell to save energy and activate a rescue program modulated by mammalian target of rapamycin (mTOR). Along with transcriptional and translational regulation, the cell relies also on post-transcriptional modulation to quickly adapt the translation of essential proteins. MicroRNAs play an important role in the regulation of protein translation, and their...

Consortium of Swiss Academic Libraries

Bioinformatics and HIV Latency

Ciuffi, Angela ; Mohammadi, Pejman ; Golumbeanu, Monica ; di Iulio, Julia ; Telenti, Amalio

In: Current HIV/AIDS Reports, 2015, vol. 12, no. 1, p. 97-106