In: Oncogene, 2021, vol. 40, no. 7, p. 1205–1216
Targeting the androgen receptor (AR) signaling axis has been, over decades, the mainstay of prostate cancer therapy. More potent inhibitors of androgen synthesis and antiandrogens have emerged and have been successfully i mplemented in clinical practice. That said, the stronger inhibition of the AR signaling axis has led in recent years to an increase of prostate cancers that de-differentiate...
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In: Acta Neuropathologica, 2015, vol. 129, no. 5, p. 679-693
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In: The Journal of Clinical Endocrinology & Metabolism, 2018, vol. 103, no. 10, p. 3748-3756
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In: Human Reproduction Update, 2016, vol. 22, no. 3, p. 382-403
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In: Human reproduction update, ///-
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In: Journal of Hematopathology, 2015, vol. 8, no. 1, p. 13-20
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In: Hormone Molecular Biology and Clinical Investigation, 2017, vol. 32, no. 1, p. -
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In: Supportive Care in Cancer, 2015, vol. 23, no. 2, p. 325-331
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In: Cancers, 2020, vol. 12, no. 10, p. 23 p
Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks effective therapeutic options. In this study, we profile eighteen TNBC cell lines for their sensitivity to the anti-proliferative action of all-trans retinoic acid (ATRA). The only three cell lines (HCC-1599, MB- 157 and MDA-MB-157) endowed with ATRA-sensitivity are characterized by genetic aberrations of the NOTCH1-gene,...
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In: PLOS ONE, 2020, vol. 15, no. 12, p. e0241500
The presence of ascites in the peritoneal cavity leads to morphological and functional changes of the peritoneal mesothelial cell layer. Cells loose cell-cell interactions, rearrange their cytoskeleton, activate the production of fibronectin, and change their cell surface morphology in a proinflammatory environment. Moreover, ovarian cancer cell adhesion has been shown to be facilitated by...
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