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Université de Fribourg

Hypoxia pathway proteins are master regulators of erythropoiesis

Watts, Deepika ; Gaete, Diana ; Rodriguez, Diego ; Hoogewijs, David ; Rauner, Martina ; Sormendi, Sundary ; Wielockx, Ben

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 21, p. 8131

Erythropoiesis is a complex process driving the production of red blood cells. During homeostasis, adult erythropoiesis takes place in the bone marrow and is tightly controlled by erythropoietin (EPO), a central hormone mainly produced in renal EPO- producing cells. The expression of EPO is strictly regulated by local changes in oxygen partial pressure (pO2) as under-deprived oxygen (hypoxia);...

Université de Fribourg

Thermal energy transport across the interface between phase change material n-heneicosane in solid and liquid phases and few-layer graphene

Chilukoti, Hari Krishna ; Zhou, Tianhang ; Ardham, Vikram Reddy ; Böhm, Michael C. ; Müller-Plathe, Florian

In: The Journal of Physical Chemistry C, 2019, vol. 123, no. 48, p. 29192–29202

Molecular dynamics simulations have been performed to investigate the mechanism of thermal energy transport at the interface between n-heneicosane in solid and liquid phases and few-layer graphene at different temperatures under two heating modes (in the “heat-matrix” mode, heat is flowing from the heated heneicosane molecules to the cooled ones through the graphene layers and in the...

Université de Fribourg

S-layer protein-AuNP systems for the colorimetric detection of metal and metalloid ions in water

Jung, J. ; Lakatos, Mathias ; Bengs, S. ; Matys, S. ; Raff, J. ; Blüher, A. ; Cuniberti, G.

In: Colloids and Surfaces B: Biointerfaces, 2019, vol. 183, p. 110284

Bacterial surface layer proteins (S-layer) possess unique binding properties for metal ions. By combining the binding capability of S-layer proteins with the optical properties of gold nanoparticles (AuNP), namely plasmonic resonance, a colorimetric detection system for metal and metalloid ions in water was developed. Eight S-layer proteins from different bacteria species were used for the...

Consortium of Swiss Academic Libraries

Explaining the heat capacity of wood constituents by molecular vibrations

Thybring, Emil

In: Journal of Materials Science, 2014, vol. 49, no. 3, p. 1317-1327

Consortium of Swiss Academic Libraries

Traditional and emerging roles for the SLC9 Na+/H+ exchangers

Fuster, Daniel ; Alexander, R.

In: Pflügers Archiv - European Journal of Physiology, 2014, vol. 466, no. 1, p. 61-76