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Autoimmmune hepatitis

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Cellular & molecular immunology, 2021, p. 19

Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all ages and characterized by female preponderance, elevated serum transaminase and immunoglobulin G levels, positive circulating autoantibodies, and presence of interface hepatitis at liver histology. AIH type 1, affecting both adults and children, is defined by positive anti- nuclear and/or antismooth muscle...

Interlaboratory variability of MIB1 staining in well-differentiated pancreatic neuroendocrine tumors

Blank, Annika ; Wehweck, Laura ; Marinoni, Ilaria ; Boos, Laura ; Bergmann, Frank ; Schmitt, Anja ; Perren, Aurel

In: Virchows Archiv, 2015, vol. 467, no. 5, p. 543-550

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

Tafti, Mehdi ; Lammers, Gert J. ; Dauvilliers, Yves ; Overeem, Sebastiaan ; Mayer, Geert ; Nowak, Jacek ; Pfister, Corinne ; Dubois, Valérie ; Eliaou, Jean-François ; Eberhard, Hans-Peter ; Liblau, Roland ; Wierzbicka, Aleksandra ; Geisler, Peter ; Bassetti, Claudio L. ; Mathis, Johannes ; Lecendreux, Michel ; Khatami, Ramin ; Heinzer, Raphaël ; Haba-Rubio, José ; Feketeova, Eva ; Baumann, Christian R. ; Kutalik, Zoltán ; Tiercy, Jean-Marie

In: Sleep, 2016, vol. 39, no. 3, p. 581-587

Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense

Boligan, Kayluz ; Mesa, Circe ; Fernandez, Luis ; von Gunten, Stephan

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 7, p. 1231-1248

HLA supertype variation across populations: new insights into the role of natural selection in the evolution of HLA-A and HLA-B polymorphisms

dos Santos Francisco, Rodrigo ; Buhler, Stéphane ; Nunes, José ; Bitarello, Bárbara ; França, Gustavo ; Meyer, Diogo ; Sanchez-Mazas, Alicia

In: Immunogenetics, 2015, vol. 67, no. 11-12, p. 651-663

Prochloraz causes irreversible masculinization of zebrafish ( Danio rerio )

Baumann, Lisa ; Knörr, Susanne ; Keiter, Susanne ; Nagel, Tina ; Segner, Helmut ; Braunbeck, Thomas

In: Environmental Science and Pollution Research, 2015, vol. 22, no. 21, p. 16417-16422

Emulsion detectors for the antihydrogen detection in AEgIS

Pistillo, C. ; Aghion, S. ; Amsler, C. ; Ariga, A. ; Ariga, T. ; Belov, A. ; Bonomi, G. ; Bräunig, P. ; Bremer, J. ; Brusa, R. ; Cabaret, L. ; Caccia, M. ; Caravita, R. ; Castelli, F. ; Cerchiari, G. ; Chlouba, K. ; Cialdi, S. ; Comparat, D. ; Consolati, G. ; Demetrio, A. ; Derking, H. ; Di Noto, L. ; Doser, M. ; Dudarev, A. ; Ereditato, A. ; Ferragut, R. ; Fontana, A. ; Gerber, S. ; Giammarchi, M. ; Gligorova, A. ; Gninenko, S. ; Haider, S. ; Hogan, S. ; Holmestad, H. ; Huse, T. ; Jordan, E. ; Kawada, J. ; Kellerbauer, A. ; Kimura, M. ; Krasnický, D. ; Lagomarsino, V. ; Lehner, S. ; Malbrunot, C. ; Mariazzi, S. ; Matveev, V. ; Mazzotta, Z. ; Nebbia, G. ; Nédélec, P. ; Oberthaler, M. ; Pacifico, N. ; Penasa, L. ; Petráček, V. ; Prelz, F. ; Prevedelli, M. ; Ravelli, L. ; Riccardi, C. ; Røhne, O. ; Rosenberger, S. ; Rotondi, A. ; Sandaker, H. ; Santoro, R. ; Scampoli, P. ; Simon, M. ; Špaček, M. ; Storey, J. ; Strojek, I. ; Subieta, M. ; Testera, G. ; Widmann, E. ; Yzombard, P. ; Zavatarelli, S. ; Zmeskal, J.

In: Hyperfine Interactions, 2015, vol. 233, no. 1-3, p. 29-34

Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance

Stolp, Bettina ; Thelen, Flavian ; Ficht, Xenia ; Altenburger, Lukas M. ; Ruef, Nora ; Inavalli, V. V. G. Krishna ; Germann, Philipp ; Page, Nicolas ; Moalli, Federica ; Raimondi, Andrea ; Keyser, Kirsten A. ; Jafari, S. Morteza Seyed ; Barone, Francesca ; Dettmer, Matthias S. ; Merkler, Doron ; Iannacone, Matteo ; Sharpe, James ; Schlapbach, Christoph ; Fackler, Oliver T. ; Nägerl, U. Valentin ; Stein, Jens V.

In: Science Immunology, 2020, vol. 5, no. 46, p. eaaz4371

It is well established that tissue macrophages and tissue-resident memory CD8+ T cells (TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. In contrast, the mechanisms by which these two cell types cooperate for homeostatic organ surveillance after clearance of infections is poorly understood. Here, we used intravital imaging to show that TRM dynamically...

The atypical receptor CCRL2 (C-C Chemokine Receptor-Like 2) does not act as a decoy receptor in endothelial cells

Mazzotti, Chiara ; Gagliostro, Vincenzo ; Bosisio, Daniela ; Del Prete, Annalisa ; Tiberio, Laura ; Thelen, Marcus ; Sozzani, Silvano

In: Frontiers in immunology, 2017, vol. 8, p. 1233

C-C chemokine receptor-like 2 (CCRL2) is a non-signaling seven-transmembrane domain (7-TMD) receptor related to the atypical chemokine receptor (ACKR) family. ACKRs bind chemokines but do not activate G protein-dependent signaling or cell functions. ACKRs were shown to regulate immune functions in vivo by their ability to scavenge chemokines from the local environment. This study was ...

Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application

Schröder, Matthias ; Arlt, Olga ; Schmidt, Helmut ; Huwiler, Andrea ; Angioni, Carlo ; Pfeilschifter, Josef M. ; Schwiebs, Anja ; Radeke, Heinfried H.

In: Biological Chemistry, 2015, vol. 396, no. 6-7, p. 795-802