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Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

Jürgens, Tanja ; Jafari, Mehrnoosh ; Kreutzfeldt, Mario ; Bahn, Erik ; Brück, Wolfgang ; Kerschensteiner, Martin ; Merkler, Doron

In: Brain, 2016, vol. 139, no. 1, p. 39-46

Healing of localized gingival recessions treated with coronally advanced flap alone or combined with either a resorbable collagen matrix or subepithelial connective tissue graft. A preclinical study

Sculean, Anton ; Mihatovic, Ilja ; Shirakata, Yoshinori ; Bosshardt, Dieter ; Schwarz, Frank ; Iglhaut, Gerhard

In: Clinical Oral Investigations, 2015, vol. 19, no. 4, p. 903-909

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

Weller, Michael ; Weber, Ruthild ; Willscher, Edith ; Riehmer, Vera ; Hentschel, Bettina ; Kreuz, Markus ; Felsberg, Jörg ; Beyer, Ulrike ; Löffler-Wirth, Henry ; Kaulich, Kerstin ; Steinbach, Joachim ; Hartmann, Christian ; Gramatzki, Dorothee ; Schramm, Johannes ; Westphal, Manfred ; Schackert, Gabriele ; Simon, Matthias ; Martens, Tobias ; Boström, Jan ; Hagel, Christian ; Sabel, Michael ; Krex, Dietmar ; Tonn, Jörg ; Wick, Wolfgang ; Noell, Susan ; Schlegel, Uwe ; Radlwimmer, Bernhard ; Pietsch, Torsten ; Loeffler, Markus ; von Deimling, Andreas ; Binder, Hans ; Reifenberger, Guido

In: Acta Neuropathologica, 2015, vol. 129, no. 5, p. 679-693

FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase

Imeri, Faik ; Blanchard, Olivier ; Jenni, Aurelio ; Schwalm, Stephanie ; Wünsche, Christin ; Zivkovic, Aleksandra ; Stark, Holger ; Pfeilschifter, Josef ; Huwiler, Andrea

In: Naunyn-Schmiedeberg's Archives of Pharmacology, 2015, vol. 388, no. 12, p. 1283-1292

Strahlenschutz im Operationssaal bei gefäßchirurgischen Eingriffen = Radiation protection in the operating theater during vascular surgery

Attigah, N. ; Knoch, T. ; Wortmann, M. ; Wieker, C. ; Geisbüsch, P. ; Böckler, D.

In: Gefässchirurgie, 2015, vol. 20, no. 4, p. 321-331

Clinical, morphological, biochemical, imaging and outcome parameters in 21 individuals with mitochondrial maintenance defect related to FBXL4 mutations

Huemer, Martina ; Karall, Daniela ; Schossig, Anna ; Abdenur, Jose ; Al Jasmi, Fatma ; Biagosch, Caroline ; Distelmaier, Felix ; Freisinger, Peter ; Graham, Brett ; Haack, Tobias ; Hauser, Natalie ; Hertecant, Jozef ; Ebrahimi-Fakhari, Darius ; Konstantopoulou, Vassiliki ; Leydiker, Karen ; Lourenco, Charles ; Scholl-Bürgi, Sabine ; Wilichowski, Ekkehard ; Wolf, Nicole ; Wortmann, Saskia ; Taylor, Robert ; Mayr, Johannes ; Bonnen, Penelope ; Sperl, Wolfgang ; Prokisch, Holger ; McFarland, Robert

In: Journal of Inherited Metabolic Disease, 2015, vol. 38, no. 5, p. 905-914

Reward-related suppression of neural activity in macaque visual area v4

Shapcott, Katharine A ; Schmiedt, Joscha T ; Kouroupaki, Kleopatra ; Kienitz, Ricardo ; Lazar, Andreea ; Singer, Wolf ; Schmid, Michael C

In: Cerebral Cortex, 2020, vol. 30, no. 9, p. 4871–4881

In order for organisms to survive, they need to detect rewarding stimuli, for example, food or a mate, in a complex environment with many competing stimuli. These rewarding stimuli should be detected even if they are nonsalient or irrelevant to the current goal. The value-driven theory of attentional selection proposes that this detection takes place through reward-associated stimuli...

Correlations in multithermostat Brownian systems with Lorentz force

Abdoli, Iman ; Kalz, Erik ; Vuijk, Hidde D. ; Wittmann, René ; Sommer, Jens-Uwe ; Brader, Joseph M. ; Sharma, Abhinav

In: New Journal of Physics, 2020, vol. 22, no. 9, p. 093057

We study the motion of a Brownian particle subjected to Lorentz force due to an external magnetic field. Each spatial degree of freedom of the particle is coupled to a different thermostat. We show that the magnetic field results in correlation between different velocity components in the stationary state. Integrating the velocity autocorrelation matrix, we obtain the diffusion matrix that...

Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice

Hauber, Ilona ; Hofmann-Sieber, Helga ; Chemnitz, Jan ; Dubrau, Danilo ; Chusainow, Janet ; Stucka, Rolf ; Hartjen, Philip ; Schambach, Axel ; Ziegler, Patrick ; Hackmann, Karl ; Schröck, Evelin ; Schumacher, Udo ; Lindner, Christoph ; Grundhoff, Adam ; Baum, Christopher ; Manz, Markus G. ; Buchholz, Frank ; Hauber, Joachim

In: Plos pathogens, 2013, vol. 9, no. 9, p. e1003587

Stable integration of HIV proviral DNA into host cell chromosomes, a hallmark and essential feature of the retroviral life cycle, establishes the infection permanently. Current antiretroviral combination drug therapy cannot cure HIV infection. However, expressing an engineered HIV-1 long terminal repeat (LTR) site-specific recombinase (Tre), shown to excise integrated proviral DNA in vitro,...

Pressure, surface tension, and curvature in active systems: A touch of equilibrium

Wittmann, René ; Smallenburg, Frank ; Brader, Joseph M.

In: The Journal of Chemical Physics, 2019, vol. 150, no. 17, p. 174908

We explore the pressure of active particles on curved surfaces and its relation to other interfacial properties. We use both direct simulations of the active systems as well as simulations of an equilibrium system with effective (pair) interactions designed to capture the effects of activity. Comparing the active and effective passive systems in terms of their bulk pressure, we elaborate that...