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Università della Svizzera italiana

Primary cutaneous cryptococcosis due to Cryptococcus neoformans in an immunocompetent host treated with itraconazole and drainage : case report and review of the literature

Gaviria Morales, Elizabeth ; Guidi, Marco ; Peterka, Thomas ; Rabufetti, Andrea ; Blum, Roland ; Mainetti, Carlo

In: Case reports in dermatology, 2021, vol. 13, no. 1, p. 89-97

Cryptococcus neoformans is an opportunistic germ, usually causing infections in immunocompromised patients. The main sources of infection with C. neoformans are excrement from birds, decomposing wood, fruit, and vegetables. Primary cutaneous cryptococcosis (PCC) is a clinical entity, differing from secondary cutaneous cryptococcosis and systematic infection. We report the case of an...

Consortium of Swiss Academic Libraries

Global access to antifungal therapy and its variable cost

Kneale, Matthew ; Bartholomew, Jennifer S. ; Davies, Emma ; Denning, David W.

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 12, p. 3599-3606

Università della Svizzera italiana

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

Sastry, Mallika ; Zhang, Baoshan ; Chen, Man ; Joyce, M. Gordon ; Kong, Wing-Pui ; Chuang, Gwo-Yu ; Ko, Kiyoon ; Kumar, Azad ; Silacci, Chiara ; Thom, Michelle ; Salazar, Andres M. ; Corti, Davide ; Lanzavecchia, Antonio ; Taylor, Geraldine ; Mascola, John R. ; Graham, Barney S. ; Kwong, Peter D.

In: Plos one, 2017, vol. 12, no. 10, p. e0186854

Appropriate adjuvant selection may be essential to optimize the potency and to tailor the immune response of subunit vaccines. To induce protective responses against respiratory syncytial virus (RSV)—a highly prevalent childhood pathogen without a licensed vaccine—we previously engineered a pre-fusion-stabilized trimeric RSV F (pre-F) “DS-Cav1” immunogen, which induced high titer...