Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.
Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...
|
In: European Archives of Psychiatry and Clinical Neuroscience, 2015, vol. 265, no. 5, p. 407-417
|
In: Acta Neurochirurgica, 2015, vol. 157, no. 9, p. 1449-1458
|
In: Ageing Research Reviews, 2019, vol. 55, p. 100956
Sensory capacities like smell, taste, hearing, vision decline with aging, but increasing evidence show that sensory dysfunctions are one of the early signs diagnosing the conversion from physiological to pathological brain state. Smell loss represents the best characterized sense in clinical practice and is considered as one of the first preclinical signs of Alzheimer’s and Parkinson’s...
|
In: Plos one, 2011, vol. 6, no. 4, p. e18268
Background: Monoclonal antibodies and antibody fragments are powerful biotherapeutics for various debilitating diseases. However, high production costs, functional limitations such as inadequate pharmacokinetics and tissue accessibility are the current principal disadvantages for broadening their use in clinic. Methodology and Principal Findings: We report a novel method for the long-term ...
|
In: Cognitive, Affective, & Behavioral Neuroscience, 2014, vol. 14, no. 3, p. 996-1008
|
In: Psychopharmacology, 2014, vol. 231, no. 19, p. 3879-3888
|
In: Brain Topography, 2014, vol. 27, no. 6, p. 801-807
|
In: Brain Topography, 2014, vol. 27, no. 3, p. 329-337
|
In: Psychophysiology, 2019, no. Special Issue: "The psychophysiology of trauma exposure", p. 1-11
|