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Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer

Alday-Parejo, Begoña ; Richard, François ; Wörthmüller, Janine ; Rau, Tilman ; Galván, José A. ; Desmedt, Christine ; Santamaria-Martinez, Albert ; Rüegg, Curzio

In: Cancers, 2020, vol. 12, no. 1, p. 223

Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...

Label-free biosensor detection of endocrine disrupting compounds using engineered estrogen receptors

La Spina, Rita ; Ferrero, Valentina E. V. ; Aiello, Venera ; Pedotti, Mattia ; Varani, Luca ; Lettieri, Teresa ; Calzolai, Luigi ; Haasnoot, Willem ; Colpo, Pascal

In: Biosensors, 2018, vol. 8, no. 1, p. 1-15

Endocrine Disrupting Compounds (EDCs) are chemical substances shown to interfere with endogenous hormones affecting the endocrine, immune and nervous systems of mammals. EDCs are the causative agents of diseases including reproductive disorders and cancers. This highlights the urgency to develop fast and sensitive methods to detect EDCs, which are detrimental even at very low concentrations....

Symptoms of endocrine treatment and outcome in the BIG 1-98 study

Huober, J. ; Cole, B. ; Rabaglio, M. ; Giobbie-Hurder, A. ; Wu, J. ; Ejlertsen, B. ; Bonnefoi, H. ; Forbes, J. ; Neven, P. ; Láng, I. ; Smith, I. ; Wardley, A. ; Price, K. ; Goldhirsch, A. ; Coates, A. ; Colleoni, M. ; Gelber, R. ; Thürlimann, B.

In: Breast Cancer Research and Treatment, 2014, vol. 143, no. 1, p. 159-169

Evaluation of reward processes in an animal model of depression

Slattery, David ; Markou, Athina ; Cryan, John

In: Psychopharmacology, 2007, vol. 190, no. 4, p. 555-568

Combined biological and chemical assessment of estrogenic activities in wastewater treatment plant effluents

Aerni, Hans-Rudolf ; Kobler, Bernd ; Rutishauser, Barbara ; Wettstein, Felix ; Fischer, René ; Giger, Walter ; Hungerbühler, Andreas ; Marazuela, M. ; Peter, Armin ; Schönenberger, René ; Vögeli, A. ; Suter, Marc ; Eggen, Rik

In: Analytical and Bioanalytical Chemistry, 2004, vol. 378, no. 3, p. 688-696

Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart

Weiss, Kilian ; Mariotti, Erika ; Hill, Deborah ; Orton, Matthew ; Dunn, Joel ; Medina, Rodolfo ; Southworth, Richard ; Kozerke, Sebastian ; Eykyn, Thomas

In: Applied Magnetic Resonance, 2012, vol. 43, no. 1-2, p. 275-288

Abstracts from the twenty-third meeting of the pancreatic society of Great Britain and Ireland at the Village Hotel, Leeds, UK

Johnson, C. ; Ammori, BJ ; Davides, D. ; Vezakis, A. ; Larvin, M. ; McMahon, KJ ; Powell, JJ ; Hill, G. ; Storey, S. ; Murchison, J. ; Fearon, K. ; Ross, J. ; Siriwardena, AK ; Pearce, NW ; Johnson, C. ; Smithies, A. ; Sargen, K. ; Demaine, A. ; Kingsnorth, A. ; Ammori, BJ ; Becker, KL ; Kite, P. ; Barclay, GR ; Snider, RH ; Nylen, ES ; White, JC ; Martin, IG ; Larvin, M. ; McMahon, MJ ; Raraty, MGT ; Ward, JB ; Vaillant, C. ; Neoptolemos, JP ; Sutton, R. ; Petersen, OH ; Creighton, J. ; Lyall, R. ; Wilson, D. ; Curtis, A. ; Charnley, R. ; Howes, N. ; Rutherford, S. ; McRonald, F. ; Ellis, I. ; Whitcomb, D. ; Mountford, R. ; Neoptolemos, JP ; Manu, M. ; Bramhall, SR ; Gur, U. ; Gunson, BK ; Le Cornu, KJ ; Mayer, AD ; Mirza, DF ; McMaster, P. ; Buckets, JAC ; King, LJ ; Bell, JRG ; Healy, J. ; Amin, Z. ; Predolac, D. ; Wotherspoon, A. ; Thompson, J. ; Norton, SA ; Alderson, D. ; Kawesha, A. ; Ghaneh, P. ; Evans, JD ; Campbell ; Dawiskiba, S. ; Lemoine, NR ; Andrén-Sandberg, A. ; Neoptolemos, JP ; Ghaneh, P. ; Humphreys, M. ; Greenhalf, W. ; Lemoine, NR ; Neoptolemos, JP ; Stoner, EA ; Piotrowicz, AJK ; Evans, DF ; Ainley, CC ; White, SA ; Pollard, C. ; Burden, AC ; Clayton, HA ; Davies, JE ; Swift, SM ; Hales, CN ; Dennison, AR ; London, NJM ; Sutton, CD ; White, S. ; Berry, DP ; Chillistone, D. ; Rees, Y. ; Dennison, AR ; Ammann, R. ; Heitz, Ph ; Klöppel, G. ; Bimmler, Daniel ; Graf, Rolf ; Frick, Thomas

In: International Journal of Pancreatology, 1999, vol. 25, no. 3, p. 229-250

Drug switch because of treatment-related adverse side effects in endocrine adjuvant breast cancer therapy: how often and how often does it work?

Güth, Uwe ; Myrick, Mary ; Schötzau, Andreas ; Kilic, Nerbil ; Schmid, Seraina

In: Breast Cancer Research and Treatment, 2011, vol. 129, no. 3, p. 799-807

Analysis of Drug/Plasma Protein Interactions by Means of Asymmetrical Flow Field-Flow Fractionation

Madörin, Maya ; van Hoogevest, Peter ; Hilfiker, Rolf ; Langwost, Birgit ; Kresbach, Gerhard ; Ehrat, Markus ; Leuenberger, Hans

In: Pharmaceutical Research, 1997, vol. 14, no. 12, p. 1706-1712

Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours

McSheehy, P. ; Port, R. ; Rodrigues, L. ; Robinson, S. ; Stubbs, M. ; van der Borns, K. ; Peters, G. ; Judson, I. ; Leach, M. ; Griffiths, J.

In: Cancer Chemotherapy and Pharmacology, 2005, vol. 55, no. 2, p. 117-128