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Université de Fribourg

Increased uptake of silica nanoparticles in inflamed macrophages but not upon co-exposure to micron-sized particles

Susnik, Eva ; Taladriz-Blanco, Patricia ; Drasler, Barbara ; Balog, Sandor ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Cells, 2020, vol. 9, no. 9, p. 2099

Silica nanoparticles (NPs) are widely used in various industrial and biomedical applications. Little is known about the cellular uptake of co-exposed silica particles, as can be expected in our daily life. In addition, an inflamed microenvironment might affect a NP’s uptake and a cell’s physiological response. Herein, prestimulated mouse J774A.1 macrophages with bacterial...

Université de Fribourg

Protein amyloid fibrils as template for the synthesis of silica nanofibers, and their use to prepare superhydrophobic, lotus-like surfaces

Rima, Simonetta ; Lattuada, Marco

In: Small, 2018, vol. 14, no. 46, p. 1802854

In this work, amyloid fibrils are used as a template for the preparation of long silica fibers, with a variety of aspect ratios and surface roughness. Starting with β‐ lactoglobulin fibrils with typical diameters of about 20 nm and a length of several micrometers, two different strategies are followed to grow silica: either in water at acidic pH values, or in ethanol–water mixtures under...