In: Future internet, 2021, vol. 13, no. 9, p. 12
As part of studies that employ health electronic records databases, this paper advocates the employment of graph theory for investigating drug-switching behaviors. Unlike the shared approach in this field (comparing groups that have switched with control groups), network theory can provide information about actual switching behavior patterns. After a brief and simple introduction to...
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In: Journal of General Internal Medicine, 2015, vol. 30, no. 8, p. 1193-1203
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In: Aesthetic Surgery Journal, 2017, vol. 37, no. 9, p. NP113-NP115
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In: Journal of Inherited Metabolic Disease, 2015, vol. 38, no. 5, p. 905-914
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In: Cerebral Cortex, 2020, vol. 30, no. 9, p. 4871–4881
In order for organisms to survive, they need to detect rewarding stimuli, for example, food or a mate, in a complex environment with many competing stimuli. These rewarding stimuli should be detected even if they are nonsalient or irrelevant to the current goal. The value-driven theory of attentional selection proposes that this detection takes place through reward-associated stimuli...
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In: Nature Reviews Drug Discovery, 2020, vol. 19, no. 10, p. 711–736
The process of poly(ADP-ribosyl)ation and the major enzyme that catalyses this reaction, poly(ADP-ribose) polymerase 1 (PARP1), were discovered more than 50 years ago. Since then, advances in our understanding of the roles of PARP1 in cellular processes such as DNA repair, gene transcription and cell death have allowed the investigation of therapeutic PARP inhibition for a variety of diseases...
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In: Bipolar Disorders, 2019, p. -
Background: Impairments in affective cognition are part of the neurocognitive profile and possible treatment targets in bipolar disorder (BD), but the findings are heterogeneous. The International Society of Bipolar Disorder (ISBD) Targeting Cognition Task Force conducted a systematic review to (i) identify the most consistent findings in affective cognition in BD, and (ii) provide...
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In: Nature communications, 2017, vol. 8, p. 1600
We have previously reported the molecular signature of murine pathogenic TH17 cells that induce experimental autoimmune encephalomyelitis (EAE) in animals. Here we show that human peripheral blood IFN-γ+IL-17+ (TH1/17) and IFN-γ−IL-17+ (TH17) CD4+ T cells display distinct transcriptional profiles in high-throughput transcription analyses. Compared to TH17 cells, TH1/17 cells have gene...
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In: Osteoporosis International, 2014, vol. 25, no. 11, p. 2531-2531
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In: Osteoporosis International, 2014, vol. 25, no. 11, p. 2507-2529
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