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Prolonged complete remission of metastatic HER2-positive breast cancer after continuous trastuzumab treatment: a case report and review of the literature

Ihnenfeld Arciénega, Isabel ; Imesch, Patrick ; Fink, Daniel ; Dedes, Konstantin

In: Targeted Oncology, 2015, vol. 10, no. 2, p. 297-301

Gender- and age-related differences in rest and post-stress left ventricular cardiac function determined by gated SPECT

Gebhard, Catherine ; Stähli, Barbara ; Gebhard, Caroline ; Fiechter, Michael ; Fuchs, Tobias ; Stehli, Julia ; Klaeser, Bernd ; Tanner, Felix ; Gaemperli, Oliver ; Kaufmann, Philipp

In: The International Journal of Cardiovascular Imaging, 2014, vol. 30, no. 6, p. 1191-1199

Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer

Lan, Qiang ; Peyvandi, Sanam ; Duffey, Nathalie ; Huang, Yu-Ting ; Barras, David ; Held, Werner ; Richard, François ; Delorenzi, Mauro ; Sotiriou, Christos ; Desmedt, Christine ; Lorusso, Girieca ; Rüegg, Curzio

In: Oncogene, 2019, vol. 38, no. 15, p. 2814–2829

Neoadjuvant and adjuvant chemotherapies provide survival benefits to breast cancer patients, in particular in estrogen receptor negative (ER−) cancers, by reducing rates of recurrences. It is assumed that the benefits of (neo)adjuvant chemotherapy are due to the killing of disseminated, residual cancer cells, however, there is no formal evidence for it. Here, we provide experimental...

A phase I clinical and pharmacological study evaluating vinflunine in combination with doxorubicin as first line treatment in metastatic breast cancer

Zaman, K. ; Durando, X. ; Baurain, J.-F ; Humblet, Y. ; Mazzeo, F. ; Bostnavaron, M. ; Meheust, N. ; Monnoyer-Favrel, S. ; Machiels, J.-P ; Bauer, J.

In: Breast Cancer Research and Treatment, 2011, vol. 127, no. 3, p. 689-696

Risk factors for chemotherapy-induced neutropenia occurrence in breast cancer patients: data from the INC-EU Prospective Observational European Neutropenia Study

Schwenkglenks, Matthias ; Pettengell, Ruth ; Jackisch, Christian ; Paridaens, Robert ; Constenla, Manuel ; Bosly, André ; Szucs, Thomas ; Leonard, Robert

In: Supportive Care in Cancer, 2011, vol. 19, no. 4, p. 483-490

Perioperative and adjuvant chemotherapy in colon cancer: results of SAKK trial 40/93

Herrmann, Richard ; Lorenz, Matthias ; Zuber, Markus ; Rufibach, Kaspar ; Laffer, Urban

In: International Journal of Colorectal Disease, 2009, vol. 24, no. 3, p. 351-352

Pathophysiology and diagnosis of cancer drug induced cardiomyopathy

Zuppinger, Christian ; Timolati, Francesco ; Suter, Thomas M.

In: Cardiovascular Toxicology, 2007, vol. 7, no. 2, p. 61-66

Human epidermal growth factor receptor 2 expression in early breast cancer patients: a Swiss cost-effectiveness analysis of different predictive assay strategies

Blank, Patricia ; Schwenkglenks, Matthias ; Moch, Holger ; Szucs, Thomas

In: Breast Cancer Research and Treatment, 2010, vol. 124, no. 2, p. 497-507

Effects of doxorubicin cancer therapy on autophagy and the ubiquitin-proteasome system in long-term cultured adult rat cardiomyocytes

Dimitrakis, Polychronis ; Romay-Ogando, Maria-Iris ; Timolati, Francesco ; Suter, Thomas ; Zuppinger, Christian

In: Cell and Tissue Research, 2012, vol. 350, no. 2, p. 361-372

Immunological response to nitroglycerin-loaded shear-responsive liposomes in vitro and in vivo

Buscema, Marzia ; Matviykiv, Sofiya ; Mészáros, Tamás ; Gerganova, Gabriela ; Weinberger, Andreas ; Mettal, Ute ; Mueller, Dennis ; Neuhaus, Frederik ; Stalder, Etienne ; Ishikawa, Takashi ; Urbanics, Rudolf ; Saxer, Till ; Pfohl, Thomas ; Szebeni, János ; Zumbuehl, Andreas ; Müller, Bert

In: Journal of Controlled Release, 2017, vol. 264, no. Supplement C, p. 14–23

Liposomes formulated from the 1,3-diamidophospholipid Pad-PC-Pad are shear- responsive and thus promising nano-containers to specifically release a vasodilator at stenotic arteries. The recommended preclinical safety tests for therapeutic liposomes of nanometer size include the in vitro assessment of complement activation and the evaluation of the associated risk of complement...