In: European Archives of Oto-Rhino-Laryngology, 2015, vol. 272, no. 7, p. 1725-1731
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In: Microbial Cell, 2019, vol. 6, no. 5, p. 212–216
GATA transcription factors (TFs) constitute a conserved family of zinc-finger TFs that fulfill diverse functions across eukaryotes. Accumulating evidence suggests that GATA TFs also play a role in lifespan regulation. In a recent study, we identified a natural polyphenol, 4,4’-dimethoxychalcone (DMC), that extends lifespan depending on reduced activity of distinct GATA TFs. Prolonged...
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In: Virchows Archiv, 2014, vol. 464, no. 3, p. 359-365
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In: The journal of clinical investigation, 2016, vol. 126, no. 3, p. 921-937
Melanoma prognosis is dictated by tumor-infiltrating lymphocytes, the migratory and functional behavior of which is guided by chemokine or cytokine gradients. Here, we retrospectively analyzed the expression patterns of 9 homing receptors (CCR/CXCR) in naive and memory CD4+ and CD8+ T lymphocytes in 57 patients with metastatic melanoma (MMel) with various sites of metastases to evaluate...
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In: Nature Communications, 2019, vol. 10, no. 1, p. 651
Ageing constitutes the most important risk factor for all major chronic ailments, including malignant, cardiovascular and neurodegenerative diseases. However, behavioural and pharmacological interventions with feasible potential to promote health upon ageing remain rare. Here we report the identification of the flavonoid 4,4′- dimethoxychalcone (DMC) as a natural compound with anti-ageing...
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In: European Radiology, 2003, vol. 13, no. 10, p. 2346-2352
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In: Neurological Sciences, 2011, vol. 32, no. 1, p. 151-153
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In: Cancer Chemotherapy and Pharmacology, 2006, vol. 57, no. 4, p. 533-539
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In: World Journal of Urology, 2007, vol. 25, no. 3, p. 297-302
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In: European Radiology, 2007, vol. 17, no. 8, p. 2160-2165
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