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Université de Fribourg

Modification of sperm fatty acid composition during epididymal maturation in bats

Fasel, Nicolas J. ; McMillian, Kevin ; Jakop, Ulrike ; Méné-Saffrané, Laurent ; Engel, Kathrin M. ; Genoud, Michel ; Müller, Karin ; Christe, Philippe

In: Reproduction, 2019, vol. 157, no. 1, p. 77–85

Biochemical properties of polyunsaturated fatty acids (PUFAs) are fundamental to sperm movements. Amongst all adjustments operated during epididymal maturation, sperm membrane lipid composition is remodelled. Specifically, the proportion of PUFAs usually increases from the caput towards the cauda epididymidis. In mammals, PUFAs are predominantly acquired through the diet, which can ...

Université de Fribourg

Characterization and potential roles of calretinin in rodent spermatozoa

Dressen, Cindy ; Schwaller, Beat ; Vegh, Grégory ; Leleux, Fabienne ; Gall, David ; Lebrun, Philippe ; Lybaert, Pascale

In: Cell Calcium, 2018, vol. 74, p. 94–101

Calretinin has been detected in various excitable cells but the presence and putative roles of such a calcium-binding protein has never been characterized in sperm.Epididymal spermatozoa were collected from C57Bl6 (wild-type, WT) or calretinin knockout (CR−/−) mice and Wistar rats. A specific staining for calretinin was detected by immunofluorescence in the principal piece of the...