In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24
Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...
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In: Basic Research in Cardiology, 2015, vol. 110, no. 1, p. 1-17
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In: Diabetologia, 2015, vol. 58, no. 2, p. 221-232
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In: Pharmacology, 2020, vol. 105, no. 9–10, p. 491–504
Background: Adipose tissue inflammation occurs not only in obesity but also in aging and is mechanistically linked with age-associated diseases. Studies show that ablation of the l-arginine-metabolizing enzyme arginase-II (Arg-II) reduces adipose tissue inflammation and improves glucose tolerance in obesity. However, the role of Arg-II in aging adipose tissue inflammation is not clear....
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In: Scientific Reports, 2020, vol. 10, no. 1, p. 11551
Zebrafish can regenerate their damaged hearts throughout their lifespan. It is, however, unknown, whether regeneration remains effective when challenged with successive cycles of cardiac damage in the same animals. Here, we assessed ventricular restoration after two, three and six cryoinjuries interspaced by recovery periods. Using transgenic cell-lineage tracing analysis, we demonstrated...
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In: European Journal of Applied Physiology, 2014, vol. 114, no. 2, p. 405-417
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In: Cellular and Molecular Life Sciences, 2014, vol. 71, no. 8, p. 1453-1467
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In: Intensive Care Medicine, 2006, vol. 32, no. 3, p. 439-444
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In: International Journal of Computer Assisted Radiology and Surgery, 2006, vol. 1, no. 4, p. 187-196
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In: Pflügers Archiv, 2004, vol. 447, no. 5, p. 480-489
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