Université de Fribourg

Embryonic photosynthesis affects post-germination plant growth

Sela, Ayala ; Piskurewicz, Urszula ; Megies, Christian ; Mène-Saffrané, Laurent ; Finazzi, Giovanni ; Lopez-Molina, Luis

In: Plant Physiology, 2020, vol. 182, no. 4, p. 2166–2181

Photosynthesis is the fundamental process fueling plant vegetative growth and development. The progeny of plants relies on maternal photosynthesis, via food reserves in the seed, to supply the necessary energy for seed germination and early seedling establishment. Intriguingly, before seed maturation, Arabidopsis (Arabidopsis thaliana) embryos are also photosynthetically active, the...

Université de Fribourg

Altering the temporal regulation of one transcription factor drives evolutionary trade-offs between head sensory organs

Ramaekers, Ariane ; Claeys, Annelies ; Kapun, Martin ; Mouchel-Vielh, Emmanuèle ; Potier, Delphine ; Weinberger, Simon ; Grillenzoni, Nicola ; Dardalhon-Cuménal, Delphine ; Yan, Jiekun ; Wolf, Reinhard ; Flatt, Thomas ; Buchner, Erich ; Hassan, Bassem A.

In: Developmental Cell, 2019, vol. 50, no. 6, p. 780-792.e7

Size trade-offs of visual versus olfactory organs is a pervasive feature of animal evolution. This could result from genetic or functional constraints. We demonstrate that head sensory organ size trade-offs in Drosophila are genetically encoded and arise through differential subdivision of the head primordium into visual versus non- visual fields. We discover that changes in the temporal...

Università della Svizzera italiana

Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses

Viejo-Borbolla, Abel ; Martinez-Martín, Nadia ; Nel, Hendrik J. ; Rueda, Patricia ; Martín, Rocío ; Blanco, Soledad ; Arenzana-Seisdedos, Fernando ; Thelen, Marcus ; Fallon, Padraic G. ; Alcamí, Antonio

In: Plos pathogens, 2012, vol. 8, no. 2, p. e1002497

Herpes simplex virus (HSV) types 1 and 2 are highly prevalent human neurotropic pathogens that cause a variety of diseases, including lethal encephalitis. The relationship between HSV and the host immune system is one of the main determinants of the infection outcome. Chemokines play relevant roles in antiviral response and immunopathology, but the modulation of chemokine function by HSV is...

Université de Fribourg

Horizons in the evolution of aging

Flatt, Thomas ; Partridge, Linda

In: BMC Biology, 2018, vol. 16, no. 1, p. 93

Between the 1930s and 50s, evolutionary biologists developed a successful theory of why organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of aging had a secure experimental basis. Since the force of selection declines with age, aging evolves due to mutation accumulation or a benefit to fitness early in life. Here we review major insights and challenges...