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Dually Active HIV/HBV Antiretrovirals as Protection Against Incident Hepatitis B Infections: Potential for Prophylaxis

Shilaih, Mohaned

In: Journal of Infectious Diseases, ///-

Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study

Kusejko, Katharina ; Kadelka, Claus ; Marzel, Alex ; Battegay, Manuel ; Bernasconi, Enos ; Calmy, Alexandra ; Cavassini, Matthias ; Hoffmann, Matthias ; Böni, Jürg ; Yerly, Sabine ; Klimkait, Thomas ; Perreau, Matthieu ; Rauch, Andri ; Günthard, Huldrych F. ; Kouyos, Roger D. ; Scherrer, Alexandra ; Wild, Susanne ; Perraudin, Danièle ; Minichiello, Mirjam ; Anagnostopoulos, A. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, D L. ; Bucher, H C. ; Calmy, A. ; Cavassini, M. ; Ciuffi, A. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, C A. ; Günthard, H F. ; Haerry, D. ; Hasse, B. ; Hirsch, H H. ; Hoffmann, M. ; Hösli, I. ; Huber, M. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R D. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K J. ; Müller, N. ; Nicca, D. ; Paioni, P. ; Pantaleo, G. ; Perreau, M. ; Rauch, A. ; Rudin, C. ; Scherrer, A U. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Wandeler, G. ; Weber, R. ; Yerly, S Morover ; Scherrer, Alexandra ; Wild, Susanne ; Perraudin, Danièle ; Minichiello, Mirjam ; Anagnostopoulos, A. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, D L. ; Bucher, H C. ; Calmy, A. ; Cavassini, M. ; Ciuffi, A. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, C A. ; Günthard, H F. ; Haerry, D. ; Hasse, B. ; Hirsch, H H. ; Hoffmann, M. ; Hösli, I. ; Huber, M. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R D. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K J. ; Müller, N. ; Nicca, D. ; Paioni, P. ; Pantaleo, G. ; Perreau, M. ; Rauch, A. ; Rudin, C. ; Scherrer, A U. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Wandeler, G. ; Weber, R. ; Yerly, S Morover

In: Virus Evolution, 2018, vol. 4, no. 2, p. -

Anti-tumor necrosis factor drug survival in axial spondyloarthritis is independent of the classification criteria

Zufferey, Pascal ; Ghosn, Jacqueline ; Becce, Fabio ; Ciurea, Adrian ; Aubry-Rozier, Bérengère ; Finckh, Axel ; So, Alexander

In: Rheumatology International, 2015, vol. 35, no. 2, p. 295-302

The potential use of microcalorimetry in rapid differentiation between septic arthritis and other causes of arthritis

Yusuf, E. ; Hügle, T. ; Daikeler, T. ; Voide, C. ; Borens, O. ; Trampuz, A.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2015, vol. 34, no. 3, p. 461-465

An MVA vector expressing HIV-1 envelope under the control of a potent vaccinia virus promoter as a promising strategy in HIV/AIDS vaccine design

Pérez, Patricia ; Marín, María Q. ; Lázaro-Frías, Adrián ; Sorzano, Carlos Óscar S. ; Di Pilato, Mauro ; Gómez, Carmen E. ; Esteban, Mariano ; García-Arriaza, Juan

In: Vaccines, 2019, vol. 7, no. 4, p. 208

Highly attenuated poxviral vectors, such as modified vaccinia virus ankara (MVA), are promising vaccine candidates against several infectious diseases. One of the approaches developed to enhance the immunogenicity of poxvirus vectors is increasing the promoter strength and accelerating during infection production levels of heterologous antigens. Here, we have generated and characterized the ...

The neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells

Gupta, Sandeep ; Gach, Johannes S. ; Becerra, Juan C. ; Phan, Tran B. ; Pudney, Jeffrey ; Moldoveanu, Zina ; Joseph, Sarah B. ; Landucci, Gary ; Supnet, Medalyn Jude ; Ping, Li-Hua ; Corti, Davide ; Moldt, Brian ; Hel, Zdenek ; Lanzavecchia, Antonio ; Ruprecht, Ruth M. ; Burton, Dennis R. ; Mestecky, Jiri ; Anderson, Deborah J. ; Forthal, Donald N.

In: Plos pathogens, 2013, vol. 9, no. 11, p. e1003776

The mechanisms by which human immunodeficiency virus type 1 (HIV-1) crosses mucosal surfaces to establish infection are unknown. Acidic genital secretions of HIV-1-infected women contain HIV-1 likely coated by antibody. We found that the combination of acidic pH and Env- specific IgG, including that from cervicovaginal and seminal fluids of HIV-1-infected individuals, augmented transcytosis...

Characterization of variable regions of the Gp120 protein from HIV-1 subtype C virus variants obtained from individuals at different disease stages in Sub-Saharan Africa

Cenci, A. ; Tavoschi, L. ; D'Avenio, G. ; Narino, P. ; Becattini, S. ; Bernasconi, D. ; Chiappi, M. ; La Torre, L. ; Sukati, H. ; Vardas, E. ; Lo Presti, A. ; Cella, E. ; Ciccozzi, M. ; Picconi, O. ; Monini, P. ; Ensoli, B. ; Buttò, S.

In: Journal of AIDS & clinical research, 2012, vol. S8:006, p. 1-10

Background: The development of a vaccine against HIV/AIDS capable of preventing virus infection has been hampered by the HIV envelope (Env) heterogeneity that makes it difficult to induce neutralizing antibodies against Env proteins from different HIV clades. Several studies have indicated that gp120 Env protein sequence tends to change considerably during the course of HIV disease which...

An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV

Watkins, Jennifer D. ; Siddappa, Nagadenahalli B. ; Lakhashe, Samir K. ; Humbert, Michael ; Sholukh, Anton ; Hemashettar, Girish ; Wong, Yin Ling ; Yoon, John K. ; Wang, Wendy ; Novembre, Francis J. ; Villinger, Francois ; Ibegbu, Chris ; Patel, Kalpana ; Corti, Davide ; Agatic, Gloria ; Vanzetta, Fabrizio ; Bianchi, Siro ; Heeney, Jonathan L. ; Sallusto, Federica ; Lanzavecchia, Antonio ; Ruprecht, Ruth M.

In: Plos one, 2011, vol. 6, no. 3, p. e18207

Neutralizing antibodies have been shown to protect macaques against SHIV challenge. However, genetically diverse HIV-1 clades have evolved, and a key question left unanswered is whether neutralizing antibodies can confer cross-clade protection in vivo. The novel human monoclonal antibody HGN194 was isolated from an individual infected with an HIV-1 clade AG recombinant circulating recombinant...

SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts

Engler, Anna ; Niederer, Fabienne ; Klein, Kerstin ; Gay, Renate ; Kyburz, Diego ; Camici, Giovanni ; Gay, Steffen ; Ospelt, Caroline

In: Journal of Molecular Medicine, 2014, vol. 92, no. 7, p. 757-767

Pour quelles raisons, le taux de transmission verticale du Virus de l'Immunodéficience Humaine (VIH) durant l'accouchement et la période du post-partum reste élevé en Afrique de l'Est, malgré les programmes de prévention actuels ? : travail de Bachelor

Dorsaz, Claire ; Héritier, Mathilde ; Carquillat, Pierre (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2018.

Introduction : Des progrès énormes ont été réalisés en matière de prévention de la transmission mère-enfant (TME) du VIH grâce à la mise en place de différents programmes en Afrique. En 2016, le taux de TME restait toutefois élevé en Afrique de l’Est. Objectif : Effectuer une revue de littérature pour déterminer quels facteurs influencent l'adhérence et l'accès aux traitements...