In: Nature, 2020, vol. 588, no. 2020-7838, p. 445–449
Pterosaurs were the first vertebrates to evolve powered flight1 and comprised one of the main evolutionary radiations in terrestrial ecosystems of the Mesozoic era (approximately 252–66 million years ago), but their origin has remained an unresolved enigma in palaeontology since the nineteenth century2,3,4. These flying reptiles have been hypothesized to be the close relatives of a wide...
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In: Proceedings of the National Academy of Sciences, 2020, vol. 117, no. 46, p. 28867–28875
Competition among species and entire clades can impact species diversification and extinction, which can shape macroevolutionary patterns. The fossil record shows successive biotic turnovers such that a dominant group is replaced by another. One striking example involves the decline of gymnosperms and the rapid diversification and ecological dominance of angiosperms in the Cretaceous. It is...
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In: MorphoMuseuM, 2020, vol. 6, no. 4, p. e118
This contribution contains the 3D surface model of the holotype cranium of the Late Jurassic thalassochelydian turtle Solnhofia brachyrhyncha described and figured in the publication of Anquetin and Püntener (2020).
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In: MorphoMuseuM, 2020, vol. 6, no. 3, p. e116
The present 3D Dataset contains two 3D models described in Tissier et al. (https://doi.org/10.1098/rsos.200633): the only known complete mandible of the early-branching rhinocerotoid Epiaceratherium magnum Uhlig, 1999, and a hypothetical reconstruction of the complete archetypic skull of Epiaceratherium Heissig, 1969, created by merging three cranial parts from three distinct Epiaceratherium...
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In: International journal of molecular sciences, 2017, vol. 18, no. 10, p. 2042
Microtubules are the main components of mitotic spindles, and are the pillars of the cellular cytoskeleton. They perform most of their cellular functions by virtue of their unique dynamic instability processes which alternate between polymerization and depolymerization phases. This in turn is driven by a precise balance between attraction and repulsion forces between the constituents of...
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In: Molecules, 2017, vol. 22, no. 8, p. 1358
The transcription factor p53 is a potent tumor suppressor dubbed as the “guardian of the genome” because of its ability to orchestrate protective biological outputs in response to a variety of oncogenic stresses. Mutation and thus inactivation of p53 can be found in 50% of human tumors. The majority are missense mutations located in the DNA binding region. Among them, G245S is known to be...
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In: Pharmaceuticals, 2018, vol. 11, no. 1, p. 22
The Toll-Like Receptor 7 (TLR7) is an endosomal membrane receptor involved in the innate immune system response. Its best-known small molecule activators are imidazoquinoline derivatives such as imiquimod (R-837) and resiquimod (R-848). Recently, an interaction between R-837 and the colchicine binding site of tubulin was reported. To investigate the possibility of an interaction between...
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In: EcoHealth, 2014, vol. 11, no. 3, p. 356-371
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In: Évaluer. Journal international de recherche en éducation et formation, 2018, vol. 4, no. 3, p. 79-103
Au début des années 2000, la province de l’Ontario a instauré un ambitieux système d’évaluation standardisée des acquis des élèves dans le but d’améliorer la performance de son système scolaire. La politique de testing ontarienne se différencie des systèmes classiques d’accountability (dure ou douce). Elle articule reddition de comptes et responsabilisation des acteurs. Au...
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In: Piotr Stanisz/Michal Zawislak/Marta Ordon (Ed.), Presence of the Cross in Public Spaces. Experiences of Selected European Countries, 2016, p. 249-261
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