Université de Fribourg

A new procyanidin B from Campylospermum zenkeri (Ochnaceae) and antiplasmodial activity of two derivatives of (±)-serotobenine

Mbabi Nyemeck II, Norbert ; Ngono Bikobo, Dominique Serge ; Zintchem, Auguste Abouem A. ; Schäfer, Eva-Maria ; Bochet, Christian G. ; Pegnyemb, Dieudonné Emmanuel ; Koert, Ulrich

In: Natural Product Research, 2017, vol. 31, no. 24, p. 2875-2884

Phytochemical investigation of the stem bark of Campylospermum zenkeri led to the isolation of five known compounds: (Z,Z)-9,12-octadecadienoic acid (1), serotobenine (2), agathisflavone (3), lophirone A (4) and lophirone F (5), together with a new derivative of procyanidin B, a catechin dimer named zenkerinol (6). Serotobenine (2) is structurally related to decursivine which shows moderate...

Université de Fribourg

Cytotoxic flavonoids and other constituents from the stem bark of Ochna schweinfurthiana

Ndongo, Joseph T. ; Issa, Mark E. ; Messi, Angelique N. ; Mbing, Joséphine Ngo ; Cuendet, Muriel ; Pegnyemb, Dieudonné Emmanuel ; Bochet, Christian G.

In: Natural Product Research, 2015, vol. 29, no. 17, p. 1684-1687

Seven flavonoids, hemerocallone (1), 6,7-dimethoxy-3′,4′-dimethoxyisoflavone (2), amentoflavone (4), agathisflavone (6), cupressuflavone (8), robustaflavone (9) and epicatechin (10), together with three other compounds, lithospermoside (3), β-D- fructofuranosyl-α-D-glucopyranoside (5) and 3β-O-D-glucopyranosyl-β-stigmasterol (7), were isolated from the ethyl acetate extract of the stem...