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Consortium of Swiss Academic Libraries

Assessment of errors caused by X-ray scatter and use of contrast medium when using CT-based attenuation correction in PET

Ay, Mohammad ; Zaidi, Habib

In: European Journal of Nuclear Medicine and Molecular Imaging, 2006, vol. 33, no. 11, p. 1301-1313

Consortium of Swiss Academic Libraries

Acquired mirroring and intentional communication in primates

Zuberbühler, Klaus

In: Language and Cognition, 2013, vol. 5, no. 2-3, p. 133-143

Université de Fribourg

Broad characterization of endogenous peptides in the tree shrew visual system

Ranc, Vaclav ; Petruzziello, Filomena ; Kretz, Robert ; Argandoña, Enrike G. ; Zhang, Xiaozhe ; Rainer, Gregor

In: Journal of Proteomics, 2012, vol. 75, no. 9, p. 2526–2535

Endogenous neuropeptides, acting as neurotransmitters or hormones in the brain, carry out important functions including neural plasticity, metabolism and angiogenesis. Previous neuropeptide studies have focused on peptide-rich brain regions such as the striatum or hypothalamus. Here we present an investigation of peptides in the visual system, composed of brain regions that are generally less...

Université de Fribourg

Autologous adult cortical cell transplantation enhances functional recovery following unilateral lesion of motor cortex in primates: a pilot study

Kaeser, Melanie ; Brunet, Jean-Francois ; Wyss, Alexander ; Belhaj-Saif, Abderraouf ; Liu, Yu ; Hamadjida, Adjia ; Rouiller, Eric M. ; Bloch, Jocelyne

In: Neurosurgery, 2011, vol. 68, no. 5, p. 1405-1417

BACKGROUND: Although cell therapy is a promising approach after cerebral cortex lesion, few studies assess quantitatively its behavioral gain in nonhuman primates. Furthermore, implantations of fetal grafts of exogenous stem cells are limited by safety and ethical issues.OBJECTIVE: To test in nonhuman primates the transplantation of autologous adult neural progenitor cortical cells with...

Université de Fribourg

Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats

Boyer, Frederic ; Dreyer, Jean-Luc

In: European Journal of Neuroscience, 2007, vol. 26, no. 10, p. 2764-2776

The mesolimbic dopaminergic system is widely recognized to be critical to the neurobiology of cocaine reward and addiction. The neuronal protein, α-synuclein, is an important regulator in dopaminergic transmission. It interacts with the dopamine transporter, and regulates dopaminergic content, neurotransmission and synaptic strength of dopaminergic neurons. Alpha-synuclein levels are elevated in...

Université de Fribourg

Adaptive coding of reward value by dopamine neurons

Tobler, Philippe N. ; Fiorillo, Christopher D. ; Schultz, Wolfram

In: Science, 2001, vol. 307, no. 5715, p. 1642-1645

It is important for animals to estimate the value of rewards as accurately as possible. Because the number of potential reward values is very large, it is necessary that the brain's limited resources be allocated so as to discriminate better among more likely reward outcomes at the expense of less likely outcomes. We found that midbrain dopamine neurons rapidly adapted to the information provided...