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Università della Svizzera italiana

Structural biology of STAT3 and its implications for anticancer therapies development

Sgrignani, Jacopo ; Garofalo, Maura ; Matkovic, Milos ; Merulla, Jessica ; Catapano, Carlo V. ; Cavalli, Andrea

In: International journal of molecular sciences, 2018, vol. 19, no. 6, p. 1591

Transcription factors are proteins able to bind DNA and induce the transcription of specific genes. Consequently, they play a pivotal role in multiple cellular pathways and are frequently over-expressed or dysregulated in cancer. Here, we will focus on a specific “signal transducer and activator of transcription” (STAT3) factor that is involved in several pathologies, including cancer....

Consortium of Swiss Academic Libraries

Law for what ails the heart: Moral frailty in Psalm 86

Lasater, Phillip Michael

In: Zeitschrift für die alttestamentliche Wissenschaft, 2015, vol. 127, no. 4, p. 652-668

Consortium of Swiss Academic Libraries

The concept of instability: a French perspective on the concept of ADHD

Bader, Michel ; Hadjikhani, Nouchine

In: ADHD Attention Deficit and Hyperactivity Disorders, 2014, vol. 6, no. 1, p. 11-17

Consortium of Swiss Academic Libraries

Towards a Modest Legal Moralism: Concept, Open Questions, and Potential Extension

Meyer, F.

In: Criminal Law and Philosophy, 2014, vol. 8, no. 1, p. 237-244

Université de Fribourg

Emplotment, Plot and Explotment : Refining Plot Analysis of Biblical Narratives from the Reader’s Perspective

Morgan, James

In: Biblical Interpretation, 2013, vol. 21, no. 1, p. 64-98

The notion of plot has a long history of various nuances and uses in literary and biblical studies. Consequently, the practice of plot analysis is quite variable. Although most definitions of plot privilege other elements than the reader, this tendency has recently begun to change. This article argues that plot is more comprehensible and constructive when it is located within the reader’s...

Consortium of Swiss Academic Libraries

Chemistry and biology of mammalian metallothioneins

Vašák, Milan ; Meloni, Gabriele

In: JBIC Journal of Biological Inorganic Chemistry, 2011, vol. 16, no. 7, p. 1067-1078

Consortium of Swiss Academic Libraries

Investigation of turbulence flow and sediment entrainment around a bridge pier

Izadinia, Elham ; Heidarpour, Manouchehr ; Schleiss, Anton

In: Stochastic Environmental Research and Risk Assessment, 2013, vol. 27, no. 6, p. 1303-1314