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Université de Fribourg

3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

Abdollahi Govar, Armita ; Törő, Gábor ; Szaniszlo, Peter ; Pavlidou, Athanasia ; Bibli, Sofia‐Iris ; Thanki, Ketan ; Resto, Vicente A. ; Chao, Celia ; Hellmich, Mark R. ; Szabo, Csaba ; Papapetropoulos, Andreas ; Módis, Katalin

In: British Journal of Pharmacology, 2020, vol. 177, no. 4, p. 866–883

During angiogenesis, quiescent endothelial cells (ECs) are activated by various stimuli to form new blood vessels from pre‐existing ones in physiological and pathological conditions. Many research groups have shown that hydrogen sulfide (H2S), the newest member of the gasotransmitter family, acts as a proangiogenic factor. To date, very little is known about the regulatory role of...

Université de Fribourg

The effect of maternal immunisation during pregnancy on infant vaccine responses

Zimmermann, Petra ; Perrett, Kirsten P. ; Messina, Nicole L. ; Donatha, Susan ; Ritz, Nicole ; Klis, Fiona R. M. van der ; Curtis, Nigel

In: EClinicalMedicine, 2019, vol. 13, p. 21–30

Immunisation during pregnancy to protect infants against tetanus, pertussis and influenza is recommended in many countries. However, maternal antibodies can interfere with infant vaccine responses. We investigated the effect of antenatal diphtheria-tetanus-acellular pertussis (dTpa) and trivalent inactivated influenza (TIV) immunisation on specific and heterologous antibody responses to...

Haute école pédagogique BEJUNE

Je ne suis pas allophone, mais… : la question de l’intégration socio-­scolaire des élèves primo-­arrivants francophones

Akamba Meke, Fréderica ; Lebrun, Marlène (Dir.)

Mémoire de bachelor : Haute école pédagogique BEJUNE, 2019.

Dans le contexte actuel de l’école, l’intégration des élèves d’origine étrangère est un défi constant pour les institutions scolaires en Suisse. Ainsi, certains dispositifs sont mis en place pour permettre aux élèves primo-arrivants allophones de pallier les difficultés qu’induit une migration. Cependant, l’intégration des élèves arrivants en Suisse, mais parlant déjà une...

Université de Neuchâtel

Kantonale Spielräume im Wandel: Migrationspolitik in der Schweiz

Probst, Johanna ; D'Amato, Gianni ; Dunning, Samantha ; Efionayi-Mäder, Denise ; Fehlmann, Joëlle ; Perret, Andreas ; Ruedin, Didier ; Sille, Irina

(SFM Studies ; 73d)

Die Schweiz hat sich verändert. Sie ist zur Heimat geworden für viele, deren Vorfahren in den letzten Jahrzehnten und Jahren von anderswo zugezogen sind. Vielfalt und Verschiedenheit – geradezu eine conditio humana der Schweiz – brauchen Verständigung über das, was uns gemeinsam ist. Dieses Bestreben, eingerahmt in einen gesellschaftlichen Prozess des Austauschs und der gegenseitigen...

Université de Neuchâtel

Représenter les étudiant-e-s extra-européen-ne-s dans le discours politique suisse (1900-2015) : garantie de compétitivité internationale ou concurrence à refréner ? = Representing non-European students in Swiss Political Discourse (1900-2015) : Guarantee of International Competitiveness or Competition to be Curbed ?

Gillabert, Matthieu ; Riaño, Yvonne

In: Géo-Regards. Revue neuchâteloise de géographie, 2017, vol. 10, p. 11-29

This article contributes to our understanding of how foreign students are represented in Swiss political discourses. It takes a historical perspective by examining how non-European students are represented in discourses mobilized at the federal level between 1900 and 2015. Students are portrayed as being either an asset or a threat. In the first case, such representations serve to legitimize...

Université de Fribourg

Biological sex influences antibody responses to routine vaccinations in the first year of life

Zimmermann, Petra ; Perrett, Kirsten P. ; Ritz,  Nicole ; Flanagan, Katie L. ; Robins-Browne, Roy ; Klis, Fiona R. M. van der ; Curtis, Nigel ; the MIS BAIR group

In: Acta Paediatrica, 2019, p. -

Aim We investigated the effect of early-life factors, namely sex, delivery mode, feeding method and antibiotic exposure, on antibody responses to routine vaccinations administered during the first year of life. Methods One and seven months after the primary course of routine vaccines and 1 month after routine vaccines at 12 months of age, antibodies against 26 vaccine antigens were measured...

Université de Neuchâtel

Memories of the "liberation of Kosovo" among Albanian-speaking activists in Switzerland : narrating transnational belonging to the nation

Farquet, Romaine ; Dahinden, Janine (Dir.) ; Duijzings, Ger (Codir.) ; Schwander-Sievers, Stephanie (Codir.) ; Lacroix, Thomas (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

The Albanian-speaking population living in Switzerland mobilised massively on behalf of the national cause in Kosovo in the 1990s. After the end of the conflict, that saw the departure of the Serbian forces from Kosovo (1999), some of the Albanian-speaking activists from Switzerland returned to their homeland. Many others remained in Switzerland, where they largely diminished or terminated their...

Université de Neuchâtel

Leaving Sri Lanka again ? : migration intentions of Sri Lankans being back from Switzerland

Stuber, Lea ; Piguet, Etienne (Dir.)

Mémoire de master : Université de Neuchâtel, 2019.

Many Sri Lankan nationals live in places outside Sri Lanka, among other reasons, due to the long-standing civil war. As the conflict ended in 2009, some of them decided ‘freely’ to return to Sri Lanka. However, others were forced to return to Sri Lanka as they weren’t granted asylum anymore. In the case of Switzerland and Sri Lanka, there exists no particular research on the social...

Università della Svizzera italiana

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

Schiraldi, Milena ; Raucci, Angela ; Martínez Muñoz, Laura ; Livoti, Elsa ; Celona, Barbara ; Venereau, Emilie ; Apuzzo, Tiziana ; De Marchis, Francesco ; Pedotti, Mattia ; Bachi, Angela ; Thelen, Marcus ; Varani, Luca ; Mellado, Mario ; Proudfoot, Amanda ; Bianchi, Marco Emilio ; Uguccioni, Mariagrazia

In: The journal of experimental medicine, 2012, vol. 209, no. 3, p. 551-563

After tissue damage, inflammatory cells infiltrate the tissue and release proinflammatory cytokines. HMGB1 (high mobility group box 1), a nuclear protein released by necrotic and severely stressed cells, promotes cytokine release via its interaction with the TLR4 (Toll-like receptor 4) receptor and cell migration via an unknown mechanism. We show that HMGB1- induced recruitment of inflammatory...

Université de Fribourg

Characterization and in vivo validation of a three-dimensional multi-cellular culture model to study heterotypic interactions in colorectal cancer cell growth, invasion and metastasis

Cattin, Sarah ; Ramont, Laurent ; Rüegg, Curzio

In: Frontiers in Bioengineering and Biotechnology, 2018, vol. 6, p. -

Colorectal cancer (CRC) is the third cause of cancer-related mortality in industrialized countries. Local invasion and metastasis formation are events associated with poor prognosis for which today there are no effective therapeutic options. Invasion and metastasis are strongly modulated by cells of the tumor microenvironment (TME), in particular fibroblasts and endothelial cells. Unraveling...