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Haute école de gestion de Genève

Risk prediction in early phases of clinical trial protocol design

Perritaz, Alex ; Teodoro, Douglas (Dir.)

Mémoire de master : Haute école de gestion de Genève, 2020 ; MASID 107.

The purpose of this study is to develop a solution able to determine the validity of a specific protocol before moving to a new stage of the clinical trial. This makes it possible to rule out ineffective protocols and to preserve financial resources. While the risks associated with the clinical trial design lead to substantial savings, they also prevent effective and promising drugs from...

Université de Fribourg

Changing the light schedule in late pregnancy alters birth timing in mice

Amano, Tomoko ; Ripperger, Jürgen A. ; Albrecht, Urs

In: Theriogenology, 2020, vol. 154, p. 212–222

In rats, birth timing is affected by changes in the light schedule until the middle of the pregnancy period. This phenomenon can be used to control birth timing in the animal industry and/or clinical fields. However, changes in the light schedule until the middle of the pregnancy period can damage the fetus by affecting the development of the major organs. Thus, we compared birth timing in...