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Haute Ecole de Gestion & Tourisme

Data mining in Bioprocesses – Knowledge discovery in databases (IIG part)

Artero, Christopher ; Schumann, René (Dir.)

Mémoire de bachelor : Haute Ecole de Gestion & Tourisme, 2021.

The purpose of this thesis is to create clusters from historical data with and without domain knowledge. The method used to cluster the data with domain knowledge is a pattern matching sequence and the method done without domain knowledge is a clustering algorithm that will be defined later. The data had to be retrieved from four old databases, then prepared to be clustered. A...

Université de Fribourg

The record of Deinotheriidae from the Miocene of the Swiss Jura Mountains (Jura Canton, Switzerland)

Gagliardi, Fanny ; Maridet, Olivier ; Becker, Damien

In: bioRxiv, 2021, p. 244061

The Miocene sands of the Swiss Jura Mountains, long exploited in quarries for the construction industry, have yielded abundant fossil remains of large mammals. Among Deinotheriidae (Proboscidea), two species, Prodeinotherium bavaricum and Deinotherium giganteum, had previously been identified in the Delémont valley, but never described. A third species, Deinotherium levius, from the locality of...

Université de Fribourg

CO and CO-releasing molecules in medicinal chemistry

Zobi, Fabio

In: Future Medicinal Chemistry, 2013, vol. 5, no. 2, p. 175-188

Since the discovery that CO acts as a cytoprotective and homeostatic molecule, increasing research efforts have been devoted to the exploitation of its therapeutic effects. Both endogenous and exogenous CO improves experimental lung, vascular and cardiac injuries and protects against several inflammatory states. The technology is now in place to bring CO to clinical applications, but the use...

Università della Svizzera italiana

The antibody response to Plasmodium falciparum : cues for vaccine design and the discovery of receptor-based antibodies

Tan, Joshua ; Piccoli, Luca ; Lanzavecchia, Antonio

In: Annual Review of Immunology

P. falciparum remains a serious public health problem and a continuous challenge for the immune system due to the complexity and diversity of the pathogen. Recent advances from several laboratories in the characterization of the antibody response to the parasite have led to the identification of critical targets for protection and revealed a new mechanism of diversification based on the...

Université de Fribourg

Phylogeny, taxonomy, and biogeography of Pterocarya (Juglandaceae)

Song, Yi-Gang ; Li, Ying ; Meng, Hong-Hu ; Fragnière, Yann ; Ge, Bin-Jie ; Sakio, Hitoshi ; Yousefzadeh, Hamed ; Bétrisey, Sébastien ; Kozlowski, Gregor

In: Plants, 2020, vol. 9, no. 11, p. 1524

Relict species play an important role in understanding the biogeography of intercontinental disjunctions. Pterocarya (a relict genus) is the valuable model taxon for studying the biogeography of East Asian versus southern European/West Asian disjunct patterns. This disjunction has not been as well studied as others (e.g., between Eastern Asia and North America). Several phylogenetic studies...

Université de Fribourg

Geochemical fingerprinting of key lithologies and depositional processes across the upper boundary of the Opalinus Clay (Aalenian, Middle Jurassic, northern Switzerland)

Lauper, Bruno ; Deplazes, Gaudenz ; Vogel, Hendrik ; Jaeggi, David ; Wohlwend, Stephan ; Ariztegui, Daniel ; Foubert, Anneleen

In: The Depositional Record, 2021, vol. 7, no. 1, p. 25-51

The Opalinus Clay is an argillaceous to silty mudstone formation, notable in Switzerland as the selected host rock for deep geological disposal of radioactive waste. Its upper bounding unit (Passwang Formation and eastern equivalents) is composed of successions of mudstone, sandy bioclastic marl and limestone separated by ooidal ironstone beds. The lithostratigraphic transition is diachronous...

Université de Fribourg

Disproportionate extinction of South American mammals drove the asymmetry of the Great American Biotic Interchange

Carrillo, Juan D. ; Faurby, Søren ; Silvestro, Daniele ; Zizka, Alexander ; Jaramillo, Carlos ; Bacon, Christine D. ; Antonelli, and Alexandre

In: Proceedings of the National Academy of Sciences, 2020, vol. 117, no. 42, p. 26281–26287

The biological interchange between North and South America associated with the formation of the Isthmus of Panama is key to defining current gradients of species diversity. A major gap in our understanding of the interchange is its asymmetry, where mammals of North American origin attained higher diversity in South America than vice versa. The prevailing view is that this asymmetry resulted...

Université de Fribourg

Emerging climate signals in the Lena River catchment: a non-parametric statistical approach

Pohl, Eric ; Grenier, Christophe ; Vrac, Mathieu ; Kageyama, Masa

In: Hydrology and Earth System Sciences, 2020, vol. 24, no. 5, p. 2817–2839

Climate change has far-reaching implications in permafrost-underlain landscapes with respect to hydrology, ecosystems, and the population's traditional livelihoods. In the Lena River catchment, eastern Siberia, changing climatic conditions and the associated impacts are already observed or expected. However, as climate change progresses the question remains as to how far we are along this...

Université de Fribourg

Anchitheriinae (Perissodactyla, Equidae) from the early middle Miocene locality Gračanica (Bugojno Basin, Bosnia-Herzegovina)

Becker, Damien ; Tissier, Jérémy ; Vasilyan, Davit ; Göhlich, Ursula B.

In: Palaeobiodiversity and Palaeoenvironments, 2020, p. -

The early middle Miocene (European Land Mammal Zone MN5-earliest MN6) locality Gračanica (Bugojno Basin, Bosnia-Herzegovina) has yielded numerous well-preserved dental remains of two Anchitheriinae species: Anchitherium hippoides and Anchitherium ezquerrae. This anchithere assemblage is typical of the Orleanian European Land Mammal Age and is recorded for the first time in Southeastern...