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Università della Svizzera italiana

Network theory and switching behaviors : a user guide for analyzing electronic records databases

Gronchi, Giorgio ; Raglianti, Marco ; Giovannelli, Fabio

In: Future internet, 2021, vol. 13, no. 9, p. 12

As part of studies that employ health electronic records databases, this paper advocates the employment of graph theory for investigating drug-switching behaviors. Unlike the shared approach in this field (comparing groups that have switched with control groups), network theory can provide information about actual switching behavior patterns. After a brief and simple introduction to...

Université de Fribourg

GPCR-based dopamine sensors—a detailed guide to inform sensor choice for in vivo imaging

Labouesse, Marie A. ; Cola, Reto B. ; Patriarchi, Tommaso

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 21, p. 8048

Understanding how dopamine (DA) encodes behavior depends on technologies that can reliably monitor DA release in freely-behaving animals. Recently, red and green genetically encoded sensors for DA (dLight, GRAB-DA) were developed and now provide the ability to track release dynamics at a subsecond resolution, with submicromolar affinity and high molecular specificity. Combined with rapid ...

Università della Svizzera italiana

Simplifying offloading applications to the network

Bressana, Pietro Giuseppe ; Soulé, Robert (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2020 ; 2020INFO011.

Recent advancements in the networking field have made the data plane fully programmable, thanks to the introduction of both programmable network architectures and network programming languages. P4, the most prominent network programming language, provides software abstractions to the components of PISA, a programmable network architecture that is able to process huge amounts of network ...

Université de Fribourg

On trends and patterns in macroevolution: Williston’s law and the branchiostegal series of extant and extinct osteichthyans

Ascarrunz, Eduardo ; Sánchez-Villagra, Marcelo R. ; Betancur, Ricardo ; Laurin, Michel

In: BMC Evolutionary Biology, 2019, vol. 19, no. 1, p. 117

The branchiostegal series consists of an alignment of bony elements in the posterior portion of the skull of osteichthyan vertebrates. We trace the evolution of the number of elements in a comprehensive survey that includes 440 extant and 66 extinct species. Using a newly updated actinopterygian tree in combination with phylogenetic comparative analyses, we test whether osteichthyan...

Université de Fribourg

Evaluation of a lifestyle change programme for the treatment of obesity in general practice

Munsch, Simone ; Biedert, Esther ; Keller, Ulrich

In: Swiss Medical Weekly, 2003, vol. 133, p. 148-154

In order to evaluate the effectiveness of a cognitive behavioural group therapy programme for the treatment of obesity in clinical practice, 122 patients from 14 general practices (n = 70) were randomised into either a treatment or a control arm with a ratio of 3 to 2. The group treatment programme was also assessed in a clinical centre (n = 52; University Hospital Basel). Before therapy, a...

Université de Fribourg

Do German Welfare-to-Work Programmes Reduce Welfare Dependency and Increase Employment?

Huber, Martin ; Lechner, Michael ; Wunsch, Conny ; Walter, Thomas

In: German economic review, 2011, vol. 12, no. 2, p. 182-204

During the last decade, many Western economies reformed their welfare systems with the aim of activating welfare recipients by increasing welfare-to-work programmes (WTWP) and job-search enforcement. We evaluate the short-term effects of three important German WTWP implemented after a major reform in January 2005 (‘Hartz IV’), namely short training, further training with a planned...