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Università della Svizzera italiana

The human Descemet's membrane and lens capsule : protein composition and biomechanical properties

Halfter, Willi ; Moes, Suzette ; Halfter, Kathrin ; Schoenenberger, Monica S. ; Monnier, Christophe A. ; Kalita, Joanna ; Asgeirsson, Daphne ; Binggeli, Tatjana ; Jenoe, Paul ; Scholl, Hendrik P.N. ; Henrich, Paul Bernhard

In: Experimental eye research, 2020, vol. 201, no. December, p. 13 p

The Descemet's membrane (DM) and the lens capsule (LC) are two ocular basement membranes (BMs) that are essential in maintaining stability and structure of the cornea and lens. In this study, we investigated the proteomes and biomechanical properties of these two materials to uncover common and unique properties. We also screened for possible protein changes during diabetes. LC-MS/MS was used...

Consortium of Swiss Academic Libraries

Finite Higher Spin Transformations from Exponentiation

Monnier, Samuel

In: Communications in Mathematical Physics, 2015, vol. 336, no. 1, p. 1-26

Université de Fribourg

Biomechanical agreement between different imitation jumps and hill jumps in ski jumping

Ketterer, Jakob ; Gollhofer, Albert ; Lauber, Benedikt

In: Scandinavian Journal of Medicine & Science in Sports, 2020, p. sms.13834

Even though the take‐off in ski jumping is decisive, athletes only have a very limited number of training trials on the actual ski jump to practice under real ski jump conditions. Hence, various imitation jumps aiming to mimic the hill jump are performed during daily training. These imitation jumps should therefore mimic the kinematic pattern of hill jumps appropriately. This study aimed to...

Université de Fribourg

Feeding biomechanics suggests progressive correlation of skull architecture and neck evolution in turtles

Ferreira, Gabriel S. ; Lautenschlager, Stephan ; Evers, Serjoscha W. ; Pfaff, Cathrin ; Kriwet, Jürgen ; Raselli, Irena ; Werneburg, Ingmar

In: Scientific Reports, 2020, vol. 10, p. 5505

The origin of turtles is one of the most long-lasting debates in evolutionary research. During their evolution, a series of modifications changed their relatively kinetic and anapsid skull into an elongated akinetic structure with a unique pulley system redirecting jaw adductor musculature. These modifications were thought to be strongly correlated to functional adaptations, especially to bite...

Université de Fribourg

No evidence that frontal optical flow affects perceived locomotor speed and locomotor biomechanics when running on a treadmill

Caramenti, Martina ; Lafortuna, Claudio L. ; Mugellini, Elena ; Khaled, Omar Abou ; Bresciani, Jean-Pierre ; Dubois, Amandine

In: Applied Sciences, 2019, vol. 9, no. 21, p. 4589

We investigated how the presentation and the manipulation of an optical flow while running on a treadmill affect perceived locomotor speed (Experiment 1) and gait parameters (Experiment 2). In Experiment 1, 12 healthy participants were instructed to run at an imposed speed and to focus on their sensorimotor sensations to be able to reproduce this running speed later. After a pause, they had...

Consortium of Swiss Academic Libraries

Quasi-static and dynamic fracture behaviour of rock materials: phenomena and mechanisms

Zhang, Q. ; Zhao, J.

In: International Journal of Fracture, 2014, vol. 189, no. 1, p. 1-32

Université de Fribourg

Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Formento, Emanuele ; Minassian, Karen ; Wagner, Fabien ; Mignardot, Jean Baptiste ; Le Goff-Mignardot, Camille G. ; Rowald, Andreas ; Bloch, Jocelyne ; Micera, Silvestro ; Capogrosso, Marco ; Courtine, Gregoire

In: Nature Neuroscience, 2018, vol. 21, no. 12, p. 1728–1741

Epidural electrical stimulation (EES) of the spinal cord restores locomotion in animal models of spinal cord injury but is less effective in humans. Here we hypothesized that this interspecies discrepancy is due to interference between EES and proprioceptive information in humans. Computational simulations and preclinical and clinical experiments reveal that EES blocks a significant amount of...

Université de Fribourg

Eliminating the VGlut2-dependent glutamatergic transmission of parvalbumin-expressing neurons leads to deficits in locomotion and vocalization, decreased pain sensitivity, and increased dominance

Roccaro-Waldmeyer, Diana M. ; Girard, Franck ; Milani, Daniele ; Vannoni, Elisabetta ; Prétôt, Laurent ; Wolfer, David P. ; Celio, Marco R.

In: Frontiers in Behavioral Neuroscience, 2018, vol. 12, p. -

The calcium-binding protein parvalbumin (PV) is a recognized marker of short-axon GABA-ergic neurons in the cortex and the hippocampus. However in addition, PV is expressed by excitatory, glutamatergic neurons in various areas of the brain and spinal cord. Depending on the location of these neurons, loading of their synaptic vesicles with glutamate is mediated by either of three vesicular...

Consortium of Swiss Academic Libraries

Topological Field Theory Interpretation of String Topology

Cattaneo, Alberto S. ; Fröhlich, Jürg ; Pedrini, Bill

In: Communications in Mathematical Physics, 2003, vol. 240, no. 3, p. 397-421