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Haute Ecole de Gestion & Tourisme

Web-based platform for managing image biomarkers

Tran, Nghi ; Depeursinge, Adrien (Dir.)

Mémoire de bachelor : Haute Ecole de Gestion & Tourisme, 2020.

The aim of this paper is to describe the process of implementing a web-based platform to manage image biomarkers, with a focus on managing and sorting datasets for machine learning. The paper will first discuss about the emerging field of radiomics, the need for a comprehensive way to manage large datasets of image biomarkers, and the current solutions in the field. This part will be the...

Université de Fribourg

Quantification of Lithological Heterogeneity Within Opalinus Clay : Toward a Uniform Subfacies Classification Scheme Using a Novel Automated Core Image Recognition Tool

Lauper, Bruno ; Zimmerli, Géraldine N. ; Jaeggi, David ; Deplazes, Gaudenz ; Wohlwend, Stephan ; Rempfer, Johannes ; Foubert, Anneleen

In: Frontiers in Earth Science, 2021, vol. 9, p. 645596

The Opalinus Clay is notable in Switzerland as being the selected host rock for deep geological disposal of radioactive waste. Since the early 1990’s, this argillaceous mudstone formation of Jurassic age has been intensively studied within the framework of national and international projects to characterize its geological, hydrological, mechanical, thermal, chemical, and biological...

Université de Fribourg

An in vitro lung system to assess the proinflammatory hazard of carbon nanotube aerosols

Barosova, Hana ; Karakocak, Bedia Begum ; Septiadi, Dedy ; Petri-Fink, Alke ; Stone, Vicki ; Rothen-Rutishauser, Barbara

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 15, p. 5335

In vitro three-dimensional (3D) lung cell models have been thoroughly investigated in recent years and provide a reliable tool to assess the hazard associated with nanomaterials (NMs) released into the air. In this study, a 3D lung co-culture model was optimized to assess the hazard potential of multiwalled carbon nanotubes (MWCNTs), which is known to provoke inflammation and fibrosis,...

Université de Fribourg

A multi-platform package for the analysis of intra- and interspecific trait evolution

Gaboriau, Théo ; Mendes, Fábio K. ; Joly, Simon ; Silvestro, Daniele ; Salamin, Nicolas

In: Methods in Ecology and Evolution, 2020, p. -

Evolutionary forces affect the distribution of phenotypes both within and among species. Yet, at the macro‐evolutionary scale, the evolution of intraspecific variance is rarely considered. Here, we present an r and a BEAST 2 implementation that extends the JIVE (Joint inter‐ and Intraspecific Variance Evolution) model aimed at the analysis of continuous trait evolution at both inter‐...

Université de Fribourg

Use of EpiAlveolar lung model to predict fibrotic potential of multiwalled carbon nanotubes

Barosova, Hana ; Maione, Anna G. ; Septiadi, Dedy ; Sharma, Monita ; Haeni, Laetitia ; Balog, Sandor ; O’Connell, Olivia ; Jackson, George R. ; Brown, David ; Clippinger, Amy J. ; Hayden, Patrick ; Petri-Fink, Alke ; Stone, Vicki ; Rothen-Rutishauser, Barbara

In: ACS Nano, 2020, vol. 14, no. 4, p. 3941–3956

Expansion in production and commercial use of nanomaterials increases the potential human exposure during the lifecycle of these materials (production, use, and disposal). Inhalation is a primary route of exposure to nanomaterials; therefore it is critical to assess their potential respiratory hazard. Herein, we developed a three-dimensional alveolar model (EpiAlveolar) consisting of human...

Université de Fribourg

Integrated bio- and cyclostratigraphy of Middle Triassic (Anisian) ramp deposits, NW Bulgaria

Ajdanlijsky, George ; Strasser, André ; Götz, Annette E.

In: Geologica Carpathica, 2019, vol. 70, no. 4, p. 325–354

A cyclostratigraphic interpretation of peritidal to shallow-marine ramp deposits of the early Middle Triassic (Anisian) Opletnya Member exposed in outcrops along the Iskar River gorge, NW Bulgaria, is presented. Based on facies trends and bounding surfaces, depositional sequences of several orders can be identified. New biostratigraphic data provide a time frame of the studied succession with...

Consortium of Swiss Academic Libraries

Cretaceous syn-sedimentary faulting in the Wildhorn Nappe (SW Switzerland)

Cardello, G. ; Mancktelow, Neil

In: Swiss Journal of Geosciences, 2014, vol. 107, no. 2-3, p. 223-250