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Università della Svizzera italiana

New shape control tools for rational Bézier curve design

Ramanantoanina, Andriamahenina ; Hormann, Kai

In: Computer aided geometric design, 2021, vol. 88, p. 11

Bézier curves are indispensable for geometric modelling and computer graphics. They have numerous favourable properties and provide the user with intuitive tools for editing the shape of a parametric polynomial curve. Even more control and flexibility can be achieved by associating a shape parameter with each control point and considering rational Bézier curves, which comes with the...

Université de Fribourg

Neuroanatomy of the spinosaurid Irritator challengeri (Dinosauria: Theropoda) indicates potential adaptations for piscivory

Schade, Marco ; Rauhut, Oliver W. M. ; Evers, Serjoscha W.

In: Scientific Reports, 2020, vol. 10, no. 1, p. 9259

Spinosauridae, a theropod group characterized by elongated snouts, conical teeth, enlarged forelimbs, and often elongated neural spines, show evidence for semiaquatic adaptations and piscivory. It is currently debated if these animals represent terrestrial carnivores with adaptations for a piscivorous diet, or if they largely lived and foraged in aquatic habitats. The holotype of Irritator...

Università della Svizzera italiana

The Mre11-Nbs1 interface is essential for viability and tumor suppression

Kim, Jun Hyun ; Grosbart, Malgorzata ; Anand, Roopesh ; Wyman, Claire ; Cejka, Petr ; Petrini, John H.J.

In: Cell reports, 2017, vol. 18, no. 2, p. 496-507

The Mre11 complex (Mre11, Rad50, and Nbs1) is integral to both DNA repair and ataxia telangiectasia mutated (ATM)-dependent DNA damage signaling. All three Mre11 complex components are essential for viability at the cellular and organismal levels. To delineate essential and non-essential Mre11 complex functions that are mediated by Nbs1, we used TALEN-based genome editing to derive Nbs1...

Université de Fribourg

Embodied semantics in a second language: critical review and clinical implications

Monaco, Elisa ; Jost, Lea B. ; Gygax, Pascal M. ; Annoni, Jean-Marie

In: Frontiers in Human Neuroscience, 2019, vol. 13, p. -

The role of the sensorimotor system in second language (L2) semantic processing as well as its clinical implications for bilingual patients has hitherto been neglected. We offer an overview of the issues at stake in this under-investigated field, presenting the theoretical and clinical relevance of studying L2 embodiment and reviewing the few studies on this topic. We highlight that (a) the...

Consortium of Swiss Academic Libraries

Book Review

Hartland, Stanley

In: Reaction Kinetics and Catalysis Letters, 2005, vol. 84, no. 2, p. 395-397