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Università della Svizzera italiana

Posterior reversible leukoencephalopathy syndrome associated with acute postinfectious glomerulonephritis : systematic review

Orlando, Corinne ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Goeggel Simonetti, Barbara ; Lava, Sebastiano A. G. ; Wyttenbach, Rolf ; Bianchetti, Mario G. ; Cristallo Lacalamita, Marirosa

In: Pediatric nephrology, 2021, p. 9

Background Kidney diseases are a recognized cause of posterior reversible leukoencephalopathy syndrome, usually abbreviated as PRES. The purpose of this review was to systematically address the association between acute postinfectious glomerulonephritis and PRES. Methods We performed a systematic review of the literature on acute postinfectious glomerulonephritis associated with PRES. The...

Università della Svizzera italiana

Willingness to vaccinate against Covid-19 : a qualitative study involving older adults from Southern Switzerland

Fadda, Marta ; Suggs, L. Suzanne ; Albanese, Emiliano

In: Vaccine: X, 2021, vol. 8, p. 7

Background: The Covid-19 pandemic is causing unprecedented disruption and suffering to people across the globe, with a disproportionate toll on the elderly. The development and equitable distribution of a vaccine seems to be the most promising and sustainable route ahead. The goal of this study was to explore older adults’ attitudes towards and beliefs regarding the Covid-19 vaccination in...

Università della Svizzera italiana

Prevalence of physiological uptake in the pancreas on somatostatin receptor-based PET/CT : a systematic review and a meta-analysis

Boughdad, Sarah ; Meyer, Marie ; Prior, John O. ; Fernandes, Victor ; Allenbach, Gilles ; Kamani, Christel ; Jreige, Mario ; Albano, Domenico ; Bertagna, Francesco ; Nicod-Lalonde, Marie ; Schaefer, Niklaus ; Treglia, Giorgio

In: Clinical and Translational Imaging, 2021, vol. 9, no. 4, p. 353–360

Background: Physiological focal radiopharmaceutical uptake in the head and uncinate process of the pancreas may be seen on somatostatin receptor-based PET/CT and might lead to false-positive results for neuroendocrine tumours (NETs). We aimed to perform a systematic review and a meta-analysis about the prevalence of this finding. Methods: We performed a comprehensive computer literature search...

Università della Svizzera italiana

Richter syndrome

Condoluci, Adalgisa ; Rossi, Davide

In: Current Oncology Reports, 2021, vol. 23, no. 3, p. 10

Purpose of Review Richter syndrome (RS) is an uncommon but aggressive evolution of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). RS is an unmet clinical need in the field of CLL. Recent advances in understanding the biology of this condition provide the rationale for testing new therapeutic concepts in order to improve the outcome of patients developing RS, which is so far...

Università della Svizzera italiana

Pre-existing cardiovascular conditions as clinical predictors of myocarditis reporting with immune checkpoint inhibitors : a VigiBase study

Noseda, Roberta ; Ruinelli, Lorenzo ; van der Gaag, Linda C. ; Ceschi, Alessandro

In: Cancers, 2020, vol. 12, no. 11, p. 15

Up to 50% of myocarditis events developed in cancer patients upon treatment with immune checkpoint inhibitors (ICIs) are fatal. Therefore, identification of clinical risk factors predicting myocarditis onset during treatment with ICIs is important for the purpose of cardiac surveillance of high-risk patients. The aim of this retrospective matched case-control study was to assess whether...

Università della Svizzera italiana

Impact of COVID-19 on the thyroid gland : an update

Scappaticcio, Lorenzo ; Pitoia, Fabián ; Esposito, Katherine ; Piccardo, Arnoldo ; Trimboli, Pierpaolo

In: Reviews in Endocrine and Metabolic Disorders, 2020, p. 13

Coronavirus disease 2019 (COVID-19) is the pandemic of the new millennium. COVID-19 can cause both pulmonary and systemic inflammation, potentially determining multi-organ dysfunction. Data on the relationship between COVID-19 and thyroid have been emerging, and rapidly increasing since March 2020. The thyroid gland and the virus infection with its associated inflammatory-immune responses are...

Università della Svizzera italiana

Dietary chloride deficiency syndrome : pathophysiology, history, and systematic literature review

Signorelli, Giulia C. ; Bianchetti, Mario G. ; Jermini, Luca M. M. ; Agostoni, Carlo ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Lava, Sebastiano A. G.

In: Nutrients, 2020, vol. 12, no. 11, p. 10 p

Metabolic alkalosis may develop as a consequence of urinary chloride (and sodium) wasting, excessive loss of salt in the sweat, or intestinal chloride wasting, among other causes. There is also a likely underrecognized association between poor salt intake and the mentioned electrolyte and acid–base abnormality. In patients with excessive loss of salt in the sweat or poor salt intake, the...

Università della Svizzera italiana

Detecting Alzheimer’s disease (AD) : from the asymptomatic stages of healthy adults with AD genetic disposition to late stages of severe neurocognitive impairment

Ibnidris, Aliaa ; Albanese, Emiliano (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.

Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...

Università della Svizzera italiana

Atypical bacterial pathogens and small-vessel leukocytoclastic vasculitis of the skin in children : systematic literature review

Betti, Céline ; Camozzi, Pietro ; Gennaro, Viola ; Bianchetti, Mario G. ; Scoglio, Martin ; Simonetti, Giacomo D. ; Milani, Gregorio P. ; Lava, Sebastiano A. G. ; Ferrarini, Alessandra

In: Pathogens, 2021, vol. 10, no. 1, p. 9 p

Leukocytoclastic small-vessel vasculitis of the skin (with or without systemic involvement) is often preceded by infections such as common cold, tonsillopharyngitis, or otitis media. Our purpose was to document pediatric (≤18 years) cases preceded by a symptomatic disease caused by an atypical bacterial pathogen. We performed a literature search following the Preferred Reporting of...

Université de Fribourg

The Co-evolution of Public Relations and Journalism : a First Contribution to Its Systematic Review = Ko-Evolution von Public Relations und Journalismus: Ein erster Beitrag zu ihrer systematischen Aufarbeitung

Schönhagen, Philomen ; Meissner, Mike

In: Public Relations Review, 2016, vol. 42, p. 748-758

There are many research findings and some theoretical models regarding the interaction between journalism and public relations (PR). But only scarce research has been done so far on the historical perspective of this relationship, which is also called co-evolution of PR and journalism. The aim of this article is to make a first step into the analysis of this co-evolution with a focus on the...