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Consortium of Swiss Academic Libraries

Global access to antifungal therapy and its variable cost

Kneale, Matthew ; Bartholomew, Jennifer S. ; Davies, Emma ; Denning, David W.

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 12, p. 3599-3606

Université de Fribourg

The rise of angiosperms pushed conifers to decline during global cooling

Condamine, Fabien L. ; Silvestro, Daniele ; Koppelhus, Eva B. ; Antonelli, Alexandre

In: Proceedings of the National Academy of Sciences, 2020, vol. 117, no. 46, p. 28867–28875

Competition among species and entire clades can impact species diversification and extinction, which can shape macroevolutionary patterns. The fossil record shows successive biotic turnovers such that a dominant group is replaced by another. One striking example involves the decline of gymnosperms and the rapid diversification and ecological dominance of angiosperms in the Cretaceous. It is...

Université de Fribourg

Disproportionate extinction of South American mammals drove the asymmetry of the Great American Biotic Interchange

Carrillo, Juan D. ; Faurby, Søren ; Silvestro, Daniele ; Zizka, Alexander ; Jaramillo, Carlos ; Bacon, Christine D. ; Antonelli, and Alexandre

In: Proceedings of the National Academy of Sciences, 2020, vol. 117, no. 42, p. 26281–26287

The biological interchange between North and South America associated with the formation of the Isthmus of Panama is key to defining current gradients of species diversity. A major gap in our understanding of the interchange is its asymmetry, where mammals of North American origin attained higher diversity in South America than vice versa. The prevailing view is that this asymmetry resulted...

Université de Fribourg

Anthropogenic climate change and glacier lake outburst flood risk: local and global drivers and responsibilities for the case of lake Palcacocha, Peru

Huggel, Christian ; Carey, Mark ; Emmer, Adam ; Frey, Holger ; Walker-Crawford, Noah ; Wallimann-Helmer, Ivo

In: Natural Hazards and Earth System Sciences, 2020, vol. 20, no. 8, p. 2175–2193

Evidence of observed negative impacts on natural and human systems from anthropogenic climate change is increasing. However, human systems in particular are dynamic and influenced by multiple drivers and hence identifying an anthropogenic climate signal is challenging. Here we analyze the case of lake Palcacocha in the Andes of Peru, which offers a representative model for other glacier lakes...

Université de Fribourg

Contribution of hydrogen cyanide to the antagonistic activity of Pseudomonas strains against Phytophthora infestans

Anand, Abhishek ; Chinchilla, Delphine ; Tan, Christopher ; Mène-Saffrané, Laurent ; L’Haridon, Floriane ; Weisskopf, Laure

In: Microorganisms, 2020, vol. 8, no. 8, p. 1144

Plants face many biotic and abiotic challenges in nature; one of them is attack by disease-causing microbes. Phytophthora infestans, the causal agent of late blight is one of the most prominent pathogens of the potato responsible for multi-billion-dollar losses every year. We have previously reported that potato-associated Pseudomonas strains inhibited P. infestans at various developmental...

Université de Fribourg

Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies

Dijkhoff, Irini M. ; Drasler, Barbara ; Karakocak, Bedia Begum ; Petri-Fink, Alke ; Valacchi, Giuseppe ; Eeman, Marc ; Rothen-Rutishauser, Barbara

In: Particle and Fibre Toxicology, 2020, vol. 17, no. 1, p. 35

Air pollution is killing close to 5 million people a year, and harming billions more. Air pollution levels remain extremely high in many parts of the world, and air pollution- associated premature deaths have been reported for urbanized areas, particularly linked to the presence of airborne nano-sized and ultrafine particles.Main text: To date, most of the research studies did focus on the...

Université de Fribourg

Selective extinction against redundant species buffers functional diversity

Pimiento, Catalina ; Bacon, Christine D. ; Silvestro, Daniele ; Hendy, Austin ; Jaramillo, Carlos ; Zizka, Alexander ; Meyer, Xavier ; Antonelli, Alexandre

In: Proceedings of the Royal Society B: Biological Sciences, 2020, vol. 287, no. 2020-1931, p. 20201162

The extinction of species can destabilize ecological processes. A way to assess the ecological consequences of species loss is by examining changes in functional diversity. The preservation of functional diversity depends on the range of ecological roles performed by species, or functional richness, and the number of species per role, or functional redundancy. However, current knowledge is...