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Università della Svizzera italiana

Electrolyte and acid-base disorders triggered by aminoglycoside or colistin therapy : a systematic review

Scoglio, Martin ; Bronz, Gabriel ; Rinoldi, Pietro O. ; Faré, Pietro B. ; Betti, Céline ; Bianchetti, Mario G. ; Simonetti, Giacomo D. ; Gennaro, Viola ; Renzi, Samuele ; Lava, Sebastiano A. G. ; Milani, Gregorio P.

In: Antibiotics, 2021, vol. 10, no. 2, p. 9

Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated. We conducted a systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses recommendations. Databases searched included United States National Library of...

Università della Svizzera italiana

Testing machine learning based systems : a systematic mapping

Riccio, Vincenzo ; Jahangirova, Gunel ; Stocco, Andrea ; Humbatova, Nargiz ; Weiss, Michael ; Tonella, Paolo

In: Empirical Software Engineering, 2020, vol. 25, no. 6, p. 5193–5254

Context: A Machine Learning based System (MLS) is a software system including one or more components that learn how to perform a task from a given data set. The increasing adoption of MLSs in safety critical domains such as autonomous driving, healthcare, and finance has fostered much attention towards the quality assurance of such systems. Despite the advances in software testing, MLSs bring...

Università della Svizzera italiana

Detecting Alzheimer’s disease (AD) : from the asymptomatic stages of healthy adults with AD genetic disposition to late stages of severe neurocognitive impairment

Ibnidris, Aliaa ; Albanese, Emiliano (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.

Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...

Université de Fribourg

Risk factors during first 1,000 days of life for carotid intima-media thickness in infants, children, and adolescents: A systematic review with meta-analyses

Epure, Adina Mihaela ; Rios-Leyvraz, Magali ; Anker, Daniela ; Di Bernardo, Stefano ; Costa, Bruno R. da ; Chiolero, Arnaud ; Sekarski, Nicole

In: PLOS Medicine, 2020, vol. 17, no. 11, p. e1003414

The first 1,000 days of life, i.e., from conception to age 2 years, could be a critical period for cardiovascular health. Increased carotid intima-media thickness (CIMT) is a surrogate marker of atherosclerosis. We performed a systematic review with meta- analyses to assess (1) the relationship between exposures or interventions in the first 1,000 days of life and CIMT in infants, children,...

Université de Fribourg

The rise of angiosperms pushed conifers to decline during global cooling

Condamine, Fabien L. ; Silvestro, Daniele ; Koppelhus, Eva B. ; Antonelli, Alexandre

In: Proceedings of the National Academy of Sciences, 2020, vol. 117, no. 46, p. 28867–28875

Competition among species and entire clades can impact species diversification and extinction, which can shape macroevolutionary patterns. The fossil record shows successive biotic turnovers such that a dominant group is replaced by another. One striking example involves the decline of gymnosperms and the rapid diversification and ecological dominance of angiosperms in the Cretaceous. It is...

Haute école de gestion de Genève

The implication of the new labor clauses in the USMCA on labor market and trade between the United States, Mexico and Canada

Stäuble, Mathieu ; Matile, Laurent (Dir.)

Mémoire de bachelor : Haute école de gestion de Genève, 2020 ; TDIBM 93.

The North American continent has implemented different free trade agreements throughout the years. From the Canadian-United States Free Trade Agreement (CUSFTA) reached in 1989, between Canada and the United States and quickly replaced by the North American Free Trade Agreement (NAFTA) in 1994 with the addition of Mexico to the agreement. After 26 years of existence and divergent opinions...

Haute école de gestion de Genève

The effectiveness of the Swiss and Canadian antibiotic distribution system compared

Janett, Sophie ; Connerton, Timothy (Dir.)

Mémoire de bachelor : Haute école de gestion de Genève, 2020 ; TDIBM 104.

The aim of research paper was to explore the current antibiotic distribution system in Switzerland, as well as all the important players of this complex industry. In order to better understand how this industry functions. It is important to get a big picture by understanding the implication of pharmaceutical companies, health insurance companies, hospitals, doctors, pharmacies and drugstores, and...

Université de Fribourg

Glossary for public health surveillance in the age of data science

Chiolero, Arnaud ; Buckeridge, David

In: J Epidemiol Community Health, 2020, vol. 74, no. 7, p. 612–616

Public health surveillance is the ongoing systematic collection, analysis and interpretation of data, closely integrated with the timely dissemination of the resulting information to those responsible for preventing and controlling disease and injury. With the rapid development of data science, encompassing big data and artificial intelligence, and with the exponential growth of accessible...