In: Experimental Astronomy, 2015, vol. 40, no. 1, p. 45-60
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In: Human Molecular Genetics, 2018, vol. 27, no. 21, p. 3825-3825
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In: Human Molecular Genetics, 2018, vol. 27, no. 12, p. 2039-2051
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In: Blood, 2020, vol. 135, no. 15, p. 1244–1254
CD49d is a remarkable prognostic biomarker of chronic lymphocytic leukemia (CLL). The cutoff value for the extensively validated 30% of positive CLL cells is able to separate CLL patients into 2 subgroups with different prognoses, but it does not consider the pattern of CD49d expression. In the present study, we analyzed a cohort of 1630 CLL samples and identified the presence of ∼20% of CLL...
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In: Autophagy, 2020, p. 1-21
Mitochondria-associated membranes (MAMs) are essential communication subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. We previously demonstrated that, upon macroautophagy/autophagy induction, AMBRA1 is recruited to the BECN1 complex and relocalizes to MAMs, where it regulates autophagy by interacting with raft-like components. ERLIN1 is an endoplasmic reticulum...
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In: Plos one, 2011, vol. 6, no. 6, p. e21386
FoxP3+ Treg cells are believed to play a role in the occurrence of autoimmunity and in the determination of clinical recurrences. Contradictory reports are, however, available describing frequency and function of Treg cells during autoimmune diseases. We examined, by both polychromatic flow cytometry, and real-time RT-PCR, several Treg markers in peripheral blood mononuclear cells from...
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In: Journal of Management & Governance, 2014, vol. 18, no. 1, p. 77-93
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In: Journal of Inherited Metabolic Disease, 2014, vol. 37, no. 5, p. 841-849
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In: Nature Communications, 2018, vol. 9, no. 1, p. 3755
The selective removal of undesired or damaged mitochondria by autophagy, known as mitophagy, is crucial for cellular homoeostasis, and prevents tumour diffusion, neurodegeneration and ageing. The pro-autophagic molecule AMBRA1 (autophagy/beclin-1 regulator-1) has been defined as a novel regulator of mitophagy in both PINK1/PARKIN-dependent and -independent systems. Here, we identified the E3...
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In: European Child & Adolescent Psychiatry, 2006, vol. 15, p. i25-i29
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