In: Nanotechnology Reviews, 2017, vol. 6, no. 1, p. 105-110
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In: The Journal of Physical Chemistry B, 2020, vol. 124, no. 38, p. 8278–8286
Lipid membranes are indispensable to life, and they regulate countless cellular processes. To investigate the properties of membranes under controlled conditions, numerous reconstitution methods have been developed over the last few decades. Several of these methods result in the formation of lipid bilayers containing residual hydrophobic molecules between the two monolayers. These...
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In: RSC Advances, 2020, vol. 10, no. 14, p. 8291–8302
Over the past decade, the rapid increase in the incidence of antibiotic-resistant bacteria has promoted research towards alternative therapeutics such as antimicrobial peptides (AMPs), but their biodegradability limits their application. Encapsulation into nanocarriers based on the self-assembly of surfactant-like lipids is emerging as a promising strategy for the improvement of AMPs'...
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In: The Journal of Physical Chemistry B, 2020, vol. 124, no. 5, p. 828–839
Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here we report on mixed bilayers of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-(1Z-...
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In: Journal of Colloid and Interface Science, 2020, vol. 562, p. 502–510
The aqueous channel size of lipidic cubic phases can be a limiting factor for certain applications. For this reason, additives have been used to exquisitely control their nanostructure. In this study, two families of primary phosphoesters have been designed, synthesised and utilised to determine the effect of the positioning of the guest additive at the interface of the host mesophase, and to...
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In: Accounts of Chemical Research, 2019, vol. 52, no. 11, p. 3087–3096
The regulatory chemical mechanisms of lipid trafficking and degradation are involved in many pathophysiological processes, being implicated in severe pain, inflammation, and cancer. In addition, the processing of lipids is also relevant for industrial and environmental applications. However, there is poor understanding of the chemical features that control lipid membrane trafficking and allow...
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In: European Biophysics Journal, 2014, vol. 43, no. 10-11, p. 517-544
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In: The Journal of Membrane Biology, 2014, vol. 247, no. 9-10, p. 965-970
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In: Physical Review B, 2019, vol. 99, no. 5, p. 054513
We report on results of our analysis of the c-axis infrared conductivity, σc(ω), of bilayer LnBa2Cu3O7−δ (Ln=La, Nd, Y) and trilayer Bi2Sr2Ca2Cu3O10+δ high-Tc superconductors. The analysis employs the multilayer model involving the conductivity of the bilayer or trilayer unit, σbl(ω), and that of the spacing layers separating the latter units, σint(ω). For the YBa2Cu3O7−δ sample...
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In: Science, 2018, vol. 362, no. 6416, p. 821–825
Ultrafast nonequilibrium dynamics offer a route to study the microscopic interactions that govern macroscopic behavior. In particular, photoinduced phase transitions (PIPTs) in solids provide a test case for how forces, and the resulting atomic motion along a reaction coordinate, originate from a nonequilibrium population of excited electronic states. Using femtosecond photoemission, we...
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