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Università della Svizzera italiana

Detecting Alzheimer’s disease (AD) : from the asymptomatic stages of healthy adults with AD genetic disposition to late stages of severe neurocognitive impairment

Ibnidris, Aliaa ; Albanese, Emiliano (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.

Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...

Université de Fribourg

Regional variation in hip and knee arthroplasty rates in Switzerland: A population-based small area analysis

Wertli, Maria M. ; Schlapbach, Judith M. ; Haynes, Alan G. ; Scheuter, Claudia ; Jegerlehner, Sabrina N. ; Panczak, Radoslaw ; Chiolero, Arnaud ; Rodondi, Nicolas ; Aujesky, Drahomir

In: PLOS ONE, 2020, vol. 15, no. 9, p. e0238287

Compared to other OECD countries, Switzerland has the highest rates of hip (HA) and knee arthroplasty (KA).Objective: We assessed the regional variation in HA/KA rates and potential determinants of variation in Switzerland.Methods: We conducted a population-based analysis using discharge data from all Swiss hospitals during 2013– 2016. We derived hospital service areas (HSAs) by analyzing...