In: Endocrine, 2015, vol. 50, no. 3, p. 821-823
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In: European Journal of Nuclear Medicine and Molecular Imaging, 2015, vol. 42, no. 1, p. 128-137
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In: Diabetologia, 2015, vol. 58, no. 2, p. 304-312
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In: Psychopharmacology, 2015, vol. 232, no. 16, p. 2981-2994
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In: Frontiers in Immunology, 2020, vol. 11, p. -
The chemokine receptor CXCR4 plays a fundamental role in homeostasis and pathology by orchestrating recruitment and positioning of immune cells, under the guidance of a CXCL12 gradient. The ability of chemokines to form heterocomplexes, enhancing their function, represents an additional level of regulation on their cognate receptors. In particular, the multi-faceted activity of the...
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In: Frontiers in immunology, 2016, vol. 7, p. 183
Chemokine biology is mediated by more complex interactions than simple monomolecular ligand–receptor interactions, as chemokines can form higher order quaternary structures, which can also be formed after binding to glycosaminoglycans (GAGs) on endothelial cells, and their receptors are found as dimers and/or oligomers at the cell surface. Due to the complexity of the chemokine binding and...
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In: Bone research, 2018, vol. 6, p. 13
Discriminating sterile inflammation from infection, especially in cases of aseptic loosening versus an actual prosthetic joint infection, is challenging and has significant treatment implications. Our goal was to evaluate a novel human monoclonal antibody (mAb) probe directed against the Gram-positive bacterial surface molecule lipoteichoic acid (LTA). Specificity and affinity were assessed in...
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In: Endocrine, 2014, vol. 47, no. 3, p. 659-661
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In: European Journal of Nuclear Medicine and Molecular Imaging, 2014, vol. 41, no. 6, p. 1166-1171
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In: European Journal of Nuclear Medicine and Molecular Imaging, 2012, vol. 39, no. 12, p. 1876-1885
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