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The effects of cardiac output and pulmonary arterial hypertension on volumetric capnography derived-variables during normoxia and hypoxia

Mosing, Martina ; Kutter, Annette ; Iff, Samuel ; Raszplewicz, Joanna ; Mauch, Jacqueline ; Bohm, Stephan ; Tusman, Gerardo

In: Journal of Clinical Monitoring and Computing, 2015, vol. 29, no. 1, p. 187-196

Effects of Exercise and Vasodilators on Cerebral Tissue Oxygenation in Pulmonary Hypertension

Müller-Mottet, Séverine ; Hildenbrand, Florian ; Keusch, Stephan ; Hasler, Elisabeth ; Maggiorini, Marco ; Speich, Rudolf ; Bloch, Konrad ; Ulrich, Silvia

In: Lung, 2015, vol. 193, no. 1, p. 113-120

A beat-by-beat analysis of cardiovascular responses to dry resting and exercise apnoeas in elite divers

Sivieri, Andrea ; Fagoni, Nazzareno ; Bringard, Aurélien ; Capogrosso, Michela ; Perini, Renza ; Ferretti, Guido

In: European Journal of Applied Physiology, 2015, vol. 115, no. 1, p. 119-128

Comparison of Sleep Disorders between Real and Simulated 3,450-m Altitude

Heinzer, Raphaël ; Saugy, Jonas J. ; Rupp, Thomas ; Tobback, Nadia ; Faiss, Raphael ; Bourdillon, Nicolas ; Rubio, José Haba ; Millet, Grégoire P.

In: Sleep, 2016, vol. 39, no. 8, p. 1517-1523

Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome

Pecze, Laszlo ; Randi, Elisa B. ; Szabo, Csaba

In: Molecular Medicine, 2020, vol. 26, no. 1, p. 102

Clinical observations and preclinical studies both suggest that Down syndrome (DS) may be associated with significant metabolic and bioenergetic alterations. However, the relevant scientific literature has not yet been systematically reviewed. The aim of the current study was to conduct a meta-analysis of metabolites involved in bioenergetics pathways in DS to conclusively determine the...

Compartment and cell-type specific hypoxia responses in the developing Drosophila brain

Baccino-Calace, Martin ; Prieto, Daniel ; Cantera, Rafael ; Egger, Boris

In: Biology Open, 2020, vol. 9, no. 8, p. -

Environmental factors such as the availability of oxygen are instructive cues that regulate stem cell maintenance and differentiation. We used a genetically encoded biosensor to monitor the hypoxic state of neural cells in the larval brain of Drosophila. The biosensor reveals brain compartment and cell-type specific levels of hypoxia. The values correlate with differential tracheolation that...

Hypoxia enhances endothelial intercellular adhesion molecule 1 protein level through upregulation of arginase type II and mitochondrial oxidative stress

Liang, Xiujie ; Arullampalam, Prakash ; Yang, Zhihong ; Ming, Xiu-Fen

In: Frontiers in Physiology, 2019, vol. 10, p. -

Hypoxia plays a crucial role in the pathogenesis of cardiovascular diseases. Mitochondrial enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance the expression of endothelial inflammatory adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). In this study, we investigate the role of Arg-II in...

Hypoxia refines plasticity of mitochondrial respiration to repeated muscle work

Desplanches, Dominique ; Amami, Myriam ; Dupré-Aucouturier, Sylvie ; Valdivieso, Paola ; Schmutz, Silvia ; Mueller, Matthias ; Hoppeler, Hans ; Kreis, Roland ; Flück, Martin

In: European Journal of Applied Physiology, 2014, vol. 114, no. 2, p. 405-417

A new interpolation-free procedure for breath-by-breath analysis of oxygen uptake in exercise transients

Bringard, Aurélien ; Adami, Alessandra ; Moia, Christian ; Ferretti, Guido

In: European Journal of Applied Physiology, 2014, vol. 114, no. 9, p. 1983-1994

Stem cells for brain repair in neonatal hypoxia-ischemia

Chicha, L. ; Smith, T. ; Guzman, R.

In: Child's Nervous System, 2014, vol. 30, no. 1, p. 37-46