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Modulation of calretinin expression in human mesothelioma cells reveals the implication of the fak and wnt signaling pathways in conferring chemoresistance towards cisplatin

Wörthmüller, Janine ; Salicio, Valérie ; Oberson, Anne ; Blum, Walter ; Schwaller, Beat

In: International Journal of Molecular Sciences, 2019, vol. 20, no. 21, p. 5391

Malignant mesothelioma (MM) is an aggressive asbestos-linked neoplasm, characterized by dysregulation of signaling pathways. Due to intrinsic or acquired chemoresistance, MM treatment options remain limited. Calretinin is a Ca2+-binding protein expressed during MM tumorigenesis that activates the FAK signaling pathway, promoting invasion and epithelial-to-mesenchymal transition. Constitutive...

Erratum to: Quantifying Protein-Ligand Binding Constants Using Electrospray Ionization Mass Spectrometry: A Systematic Binding Affinity Study of a Series of Hydrophobically Modified Trypsin Inhibitors

Cubrilovic, Dragana ; Biela, Adam ; Sielaff, Frank ; Steinmetzer, Torsten ; Klebe, Gerhard ; Zenobi, Renato

In: Journal of The American Society for Mass Spectrometry, 2014, vol. 25, no. 7, p. 1305-1305

Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924

Megger, Dominik Andre ; Abou-Eid, Shadi ; Zülch, Birgit ; Sitek, Barbara

In: Molecular Omics, 2018, vol. 14, no. 6, p. 450–457

Chemotherapeutic treatment regimens often take advantage of synergistic effects of drug combinations. Anticipating that synergistic effects on the cell biological level likely manifest on the proteome level, the analysis of proteome modulations represents an appropriate strategy to study drug combinations on a molecular level. More specifically, the detection of single proteins exhibiting...

Thermal Deamination-anation in Cobalt(III) Thiocyanate Complexes. Novel decarbonylation of the equatorial amide ligand

Amirnasr, M. ; Houriet, R. ; Meghdadi, S.

In: Journal of Thermal Analysis and Calorimetry, 2002, vol. 67, no. 3, p. 523-533

Chemistry and biology of mammalian metallothioneins

Vašák, Milan ; Meloni, Gabriele

In: JBIC Journal of Biological Inorganic Chemistry, 2011, vol. 16, no. 7, p. 1067-1078

Quantifying Protein-Ligand Binding Constants using Electrospray Ionization Mass Spectrometry: A Systematic Binding Affinity Study of a Series of Hydrophobically Modified Trypsin Inhibitors

Cubrilovic, Dragana ; Biela, Adam ; Sielaff, Frank ; Steinmetzer, Torsten ; Klebe, Gerhard ; Zenobi, Renato

In: Journal of The American Society for Mass Spectrometry, 2012, vol. 23, no. 10, p. 1768-1777

Functionally Important Residues in the Predicted 3rd Transmembrane Domain of the Type IIa Sodium-phosphate Cotransporter (NaPi-IIa)

Virkki, L.V. ; Forster, I.C. ; Bacconi, A. ; Biber, J. ; Murer, H.

In: The Journal of Membrane Biology, 2005, vol. 206, no. 3, p. 227-238

The metal-binding properties of the blue crab copper specific CuMT-2: a crustacean metallothionein with two cysteine triplets

Serra-Batiste, Montserrat ; Cols, Neus ; Alcaraz, Luis ; Donaire, Antonio ; González-Duarte, Pilar ; Vašák, Milan

In: JBIC Journal of Biological Inorganic Chemistry, 2010, vol. 15, no. 5, p. 759-776

Influence of $$ {\text{NH - }}{{\text{S}}^\gamma } $$ bonding interactions on the structure and dynamics of metallothioneins

Romero-Isart, Núria ; Oliva, Baldo ; Vašák, Milan

In: Journal of Molecular Modeling, 2010, vol. 16, no. 3, p. 387-394

Vitamin B12 as a carrier for targeted platinum delivery: in vitro cytotoxicity and mechanistic studies

Ruiz-Sánchez, Pilar ; König, Christiane ; Ferrari, Stefano ; Alberto, Roger

In: JBIC Journal of Biological Inorganic Chemistry, 2011, vol. 16, no. 1, p. 33-44