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Dexamethasone induces changes in osteogenic differentiation of human mesenchymal stromal cells via SOX9 and PPARG, but not RUNX2

Della Bella, Elena ; Buetti-Dinh, Antoine ; Licandro, Ginevra ; Ahmad, Paras ; Basoli, Valentina ; Alini, Mauro ; Stoddart, Martin J.

In: International journal of molecular sciences, 2021, vol. 22, no. 9, p. 16

Despite the huge body of research on osteogenic differentiation and bone tissue engineering, the translation potential of in vitro results still does not match the effort employed. One reason might be that the protocols used for in vitro research have inherent pitfalls. The synthetic glucocorticoid dexamethasone is commonly used in protocols for trilineage differentiation of human bone marrow...

Molecular and cellular basis of bone resorption = Anatomy and biochemistry of the osteoclast

Gruber, Reinhard

In: Wiener Medizinische Wochenschrift, 2015, vol. 165, no. 3-4, p. 48-53

Effect of bone graft density on in vitro cell behavior with enamel matrix derivative

Miron, Richard ; Caluseru, Oana ; Guillemette, Vincent ; Zhang, Yufeng ; Buser, Daniel ; Chandad, Fatiha ; Sculean, Anton

In: Clinical Oral Investigations, 2015, vol. 19, no. 7, p. 1643-1651

Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells

Barrio-Hernandez, Inigo ; Jafari, Abbas ; Rigbolt, Kristoffer T.G. ; Hallenborg, Philip ; Sanchez-Quiles, Virginia ; Skovrind, Ida ; Akimov, Vyacheslav ; Kratchmarova, Irina ; Dengjel, Jörn ; Kassem, Moustapha ; Blagoev, Blagoy

In: Genome Research, 2020, vol. 30, no. 1, p. 127-137

Bone marrow–derived mesenchymal stem cells (MSCs) differentiate into osteoblasts upon stimulation by signals present in their niche. Because the global signaling cascades involved in the early phases of MSCs osteoblast (OB) differentiation are not well-defined, we used quantitative mass spectrometry to delineate changes in human MSCs proteome and phosphoproteome during the first 24 h of...

SPECT/CT for imaging of the spine and pelvis in clinical routine: a physician's perspective of the adoption of SPECT/CT in a clinical setting with a focus on trauma surgery

Scheyerer, Max ; Pietsch, Carsten ; Zimmermann, Stefan ; Osterhoff, Georg ; Simmen, Hans-Peter ; Werner, Clement

In: European Journal of Nuclear Medicine and Molecular Imaging, 2014, vol. 41, p. 59-66

Osteoanabolic effect of alendronate and zoledronate on bone marrow stromal cells (BMSCs) isolated from aged female osteoporotic patients and its implications for their mode of action in the treatment of age-related bone loss

Lindtner, R. ; Tiaden, A. ; Genelin, K. ; Ebner, H. ; Manzl, C. ; Klawitter, M. ; Sitte, I. ; von Rechenberg, B. ; Blauth, M. ; Richards, P.

In: Osteoporosis International, 2014, vol. 25, no. 3, p. 1151-1161

In vitro characterization of a synthetic calcium phosphate bone graft on periodontal ligament cell and osteoblast behavior and its combination with an enamel matrix derivative

Miron, Richard ; Bosshardt, Dieter ; Gemperli, Anja ; Dard, Michel ; Buser, Daniel ; Gruber, Reinhard ; Sculean, Anton

In: Clinical Oral Investigations, 2014, vol. 18, no. 2, p. 443-451

Phosphate homeostasis in Bartter syndrome: a case-control study

Bettinelli, Alberto ; Viganò, Cristina ; Provero, Maria ; Barretta, Francesco ; Albisetti, Alessandra ; Tedeschi, Silvana ; Scicchitano, Barbara ; Bianchetti, Mario

In: Pediatric Nephrology, 2014, vol. 29, no. 11, p. 2133-2138

Effects of serum and serum heat-inactivation on human bone derived osteoblast progenitor cells

Bruinink, A. ; Tobler, U. ; Hälg, M. ; Grünert, J.

In: Journal of Materials Science: Materials in Medicine, 2004, vol. 15, no. 4, p. 497-501

Osteoblast proliferation and differentiation on a barrier membrane in combination with BMP2 and TGFβ1

Miron, Richard ; Saulacic, Nikola ; Buser, Daniel ; Iizuka, Tateyuki ; Sculean, Anton

In: Clinical Oral Investigations, 2013, vol. 17, no. 3, p. 981-988