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An immature B cell population from peripheral blood serves as surrogate marker for monitoring tumor angiogenesis and anti-angiogenic therapy in mouse models

Fagiani, Ernesta ; Bill, Ruben ; Pisarsky, Laura ; Ivanek, Robert ; Rüegg, Curzio ; Christofori, Gerhard

In: Angiogenesis, 2015, vol. 18, no. 3, p. 327-345

Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense

Boligan, Kayluz ; Mesa, Circe ; Fernandez, Luis ; von Gunten, Stephan

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 7, p. 1231-1248

Targeting sialic acid-Siglec interactions to reverse immune suppression in cancer

Adams, Olivia Joan ; Stanczak, Michal A. ; von Gunten, Stephan ; Läubli, Heinz

In: Glycobiology, 2018, vol. 28, no. 9, p. 640-647

The antibody-mediated targeted delivery of interleukin-13 to syngeneic murine tumors mediates a potent anticancer activity

Hess, Christian ; Neri, Dario

In: Cancer Immunology, Immunotherapy, 2015, vol. 64, no. 5, p. 635-644

Formation and role of exosomes in cancer

Brinton, Lindsey ; Sloane, Hillary ; Kester, Mark ; Kelly, Kimberly

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 4, p. 659-671

Morphological and molecular characteristics of HER2 amplified urothelial bladder cancer

Tschui, J. ; Vassella, E. ; Bandi, N. ; Baumgartner, U. ; Genitsch, V. ; Rotzer, D. ; Seiler, R. ; Thalmann, G. ; Fleischmann, A.

In: Virchows Archiv, 2015, vol. 466, no. 6, p. 703-710

Sialic acids in cancer biology and immunity

Pearce, Oliver M T. ; Läubli, Heinz

In: Glycobiology, 2016, vol. 26, no. 2, p. 111-128

Doppler Ultrasound Flow Evaluation of the Uterine Arteries Significantly Correlates with Tumor Size in Cervical Cancer Patients

Bolla, Daniele ; In-Albon, Sarah ; Papadia, Andrea ; Di Naro, Edoardo ; Gasparri, Maria ; Mueller, Michael ; Raio, Luigi

In: Annals of Surgical Oncology, 2015, vol. 22, p. 959-963

The patent buyout price for human papilloma virus (HPV) vaccine and the ratio of R&D costs to the patent value

Songane, Mario ; Grossmann, Volker

In: PLOS One, 2021, p. 1-22

Human papillomavirus (HPV) is responsible for almost all of the 570,000 new cases of cervical cancer and approximately 311,000 deaths per year. HPV vaccination is an integral component of the World Health Organization’s (WHO) global strategy to fight the disease. However, high vaccine prices enforced through patent protection are limiting vaccine expansion, particularly in low- and...

CD49d promotes disease progression in chronic lymphocytic leukemia : new insights from CD49d bimodal expression

Tissino, Erika ; Pozzo, Federico ; Benedetti, Dania ; Caldana, Chiara ; Bittolo, Tamara ; Rossi, Francesca Maria ; Bomben, Riccardo ; Nanni, Paola ; Chivilò, Hillarj ; Cattarossi, Ilaria ; Zaina, Eva ; Norris, Kevin ; Polesel, Jerry ; Gentile, Massimo ; Tripepi, Giovanni ; Moia, Riccardo ; Santinelli, Enrico ; Innocenti, Idanna ; Olivieri, Jacopo ; D’Arena, Giovanni ; Laurenti, Luca ; Zaja, Francesco ; Pozzato, Gabriele ; Chiarenza, Annalisa ; Di Raimondo, Francesco ; Rossi, Davide ; Pepper, Chris ; Hartmann, Tanja Nicole ; Gaidano, Gianluca ; Del Poeta, Giovanni ; Gattei, Valter ; Zucchetto, Antonella

In: Blood, 2020, vol. 135, no. 15, p. 1244–1254

CD49d is a remarkable prognostic biomarker of chronic lymphocytic leukemia (CLL). The cutoff value for the extensively validated 30% of positive CLL cells is able to separate CLL patients into 2 subgroups with different prognoses, but it does not consider the pattern of CD49d expression. In the present study, we analyzed a cohort of 1630 CLL samples and identified the presence of ∼20% of CLL...