In: Clinical reviews in allergy & immunology, 2021, p. 14
Circulating autoantibodies are a key diagnostic tool in autoimmune hepatitis (AIH), being positive in 95% of the cases if tested according to dedicated guidelines issued by the International Autoimmune Hepatitis Group. They also allow the distinction between type 1 AIH, characterized by positive anti-nuclear and/or anti-smooth muscle antibody, and type 2 AIH, characterized by positive...
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In: Digestive Diseases and Sciences, 2015, vol. 60, no. 2, p. 485-491
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In: World Journal of Surgery, 2015, vol. 39, no. 9, p. 2274-2281
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In: Current Infectious Disease Reports, 2015, vol. 17, no. 4, p. 1-11
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In: European Journal of Pediatrics, 2015, vol. 174, no. 2, p. 151-167
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In: World Journal of Surgery, 2015, vol. 39, no. 10, p. 2529-2534
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In: Nature communications, 2015, vol. 6, p. 6163
Glycoprotein G (gG) from herpes simplex virus 1 and 2 (HSV-1 and HSV-2, important human neurotropic pathogens) is the first viral chemokine-binding protein found to potentiate chemokine function. Here we show that gG attaches to cell surface glycosaminoglycans and induces lipid raft clustering, increasing the incorporation of CXCR4 receptors into these microdomains. gG induces conformational...
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In: Plos pathogens, 2012, vol. 8, no. 2, p. e1002497
Herpes simplex virus (HSV) types 1 and 2 are highly prevalent human neurotropic pathogens that cause a variety of diseases, including lethal encephalitis. The relationship between HSV and the host immune system is one of the main determinants of the infection outcome. Chemokines play relevant roles in antiviral response and immunopathology, but the modulation of chemokine function by HSV is...
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In: Infection, 2014, vol. 42, no. 4, p. 779-783
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In: Digestive Diseases and Sciences, 2014, vol. 59, no. 9, p. 2058-2068
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