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Università della Svizzera italiana

Detecting Alzheimer’s disease (AD) : from the asymptomatic stages of healthy adults with AD genetic disposition to late stages of severe neurocognitive impairment

Ibnidris, Aliaa ; Albanese, Emiliano (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.

Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...

Université de Fribourg

Ecological Monitoring and Management App (EMMA) for Older Adults With Chronic Pain: Protocol for a Design and Feasibility Study

Ledermann, Katharina ; Abou Khaled, Omar ; Caon, Maurizio ; Berger, Thomas ; Chabwine, Joelle ; Martin-Soelch, Chantal

In: JMIR Research Protocols

Background: Chronic pain is a complex problem for many older adults that affects both physical functioning and psychological well-being. Mobile health (mHealth) technologies have shown promise in supporting older persons in managing chronic conditions. Cognitive behavior therapy (CBT) is recommended for older people with chronic pain. However, online treatment programs for chronic pain are...

Université de Fribourg

Striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: A preliminary study

Gaillard, Claudie ; Guillod, Matthias ; Ernst, Monique ; Federspiel, Andrea ; Schoebi, Dominik ; Recabarren, Romina Evelyn ; Ouyang, Xinyi ; Mueller-Pfeiffer, Christoph ; Horschg, Antje ; Homan, Philipp ; Wiest, Roland ; Hasler, Gregor ; Martin-Soelch, Chantal

In: NeuroImage: Clinical, 2020, vol. 26, p. 102193

Introduction: Anhedonia, a core symptom of Major Depressive Disorder (MDD), manifests as a lack or loss of motivation as reflected by decreased reward responsiveness, at both behavioral and neural (i.e., striatum) levels. Exposure to stressful life events is another important risk factor for MDD. However, the mechanisms linking reward-deficit and stress to MDD remain poorly understood. Here,...

Université de Fribourg

A Language Index of Grammatical Gender Dimensions to Study the Impact of Grammatical Gender on the Way We Perceive Women and Men

Gygax, Pascal ; Elmiger, Daniel ; Zufferey, Sandrine ; Garnham, Alan ; Sczesny, Sabine ; von Stockhausen, Lisa ; Braun, Friederike ; Oakhill, Jane

In: Frontiers in Psychology, 2019, vol. 10, no. 1604, p. 1-6

Psycholinguistic investigations of the way readers and speakers perceive gender have shown several biases associated with how gender is linguistically realized in language. Although such variations across languages offer interesting grounds for legitimate cross- linguistic comparisons, pertinent characteristics of grammatical systems – especially in terms of their gender asymmetries –...